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[针对孕妇及备孕女性的疫苗接种]

[Vaccinations for pregnant women and women attempting to become pregnant].

作者信息

Tempfer Clemens

机构信息

Klinik für Frauenheilkunde, Marien Hospital Herne - Universitätsklinikum der Ruhr-Universität Bochum, Hölkeskampring 40, 44625 Herne, Deutschland.

出版信息

Gynakol Endokrinol. 2022;20(2):93-100. doi: 10.1007/s10304-022-00439-5. Epub 2022 Feb 1.

Abstract

Infectious diseases are a potential source of maternal and fetal morbidity and mortality. Every pregnant woman, as well as women actively attempting to become pregnant, should seek specific counselling regarding immunization recommendations. If pregnant women or women attempting to become pregnant plan long-distance travel, immunization requirements should be discussed, especially if their travel destination is within an area endemic for diseases such as malaria, yellow fever, tuberculosis, hepatitis, human immunodeficiency virus-associated diseases, leishmaniosis, toxoplasmosis, and Japanese encephalitis. In general, toxoid vaccinations, inactivated vaccinations, and immunoglobulins can be safely administered during pregnancy, whereas live vaccinations are contraindicated. Recommended vaccinations during pregnancy include tetanus, diphtheria, and pertussis in the case of insufficient immunization status, as well as the seasonal influenza vaccination and-during the current pandemic-coronavirus disease 19 (COVID-19) vaccination in the 2nd or 3rd trimester. Specific travel vaccinations are those against rotavirus, tetanus, diphtheria, pertussis, type B, polio, hepatitis B, pneumococcus, meningococcus, measles, mumps, rubella, varicella, human papilloma virus (HPV), and influenza (if not already properly vaccinated). In addition, hepatitis A, yellow fever, and polio are recommended in certain countries with endemic areas according to World Health Organization specifications. Some countries may have additional vaccination regulations regarding cholera and meningococcus. Vaccinations "per indication" are required if the travel destination is an area with specific locally increased risks.

摘要

传染病是孕产妇和胎儿发病及死亡的潜在来源。每位孕妇以及积极备孕的女性都应就免疫接种建议寻求专业咨询。如果孕妇或备孕女性计划长途旅行,应讨论免疫接种要求,特别是当她们的旅行目的地是疟疾、黄热病、结核病、肝炎、人类免疫缺陷病毒相关疾病、利什曼病、弓形虫病和日本脑炎等疾病的流行地区时。一般来说,类毒素疫苗、灭活疫苗和免疫球蛋白在孕期可以安全接种,而活疫苗则禁忌接种。孕期推荐接种的疫苗包括免疫状况不足时的破伤风、白喉和百日咳疫苗,以及季节性流感疫苗,在当前大流行期间,还包括孕中期或孕晚期的新型冠状病毒肺炎(COVID-19)疫苗。特定的旅行疫苗包括针对轮状病毒、破伤风、白喉、百日咳、B型流感嗜血杆菌、脊髓灰质炎、乙型肝炎、肺炎球菌、脑膜炎球菌、麻疹、腮腺炎、风疹、水痘、人乳头瘤病毒(HPV)和流感(如果尚未正确接种)的疫苗。此外,根据世界卫生组织的规范,在某些流行地区的国家,还推荐接种甲型肝炎、黄热病和脊髓灰质炎疫苗。一些国家可能对霍乱和脑膜炎球菌有额外的疫苗接种规定。如果旅行目的地是当地风险特别增加的地区,则需要“根据指征”进行疫苗接种。

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Receipt of mRNA Covid-19 Vaccines and Risk of Spontaneous Abortion.接受新冠病毒mRNA疫苗与自然流产风险
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Preliminary Findings of mRNA Covid-19 Vaccine Safety in Pregnant Persons.mRNA 新冠疫苗在孕妇中的初步安全性研究结果。
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Zika Virus Infection in Pregnant Women in Rio de Janeiro.里约热内卢孕妇的寨卡病毒感染情况
N Engl J Med. 2016 Dec 15;375(24):2321-2334. doi: 10.1056/NEJMoa1602412. Epub 2016 Mar 4.
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Zika Virus in the Americas--Yet Another Arbovirus Threat.美洲的寨卡病毒——又一种虫媒病毒威胁
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