Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States.
J Chem Inf Model. 2022 Feb 28;62(4):753-760. doi: 10.1021/acs.jcim.1c01461. Epub 2022 Feb 7.
BINding ANAlyzer (BINANA) is an algorithm for identifying and characterizing receptor/ligand interactions and other factors that contribute to binding. We recently updated BINANA to make the algorithm more accessible to a broader audience. We have also ported the Python3 codebase to JavaScript, thus enabling BINANA analysis in the web browser. As proof of principle, we created a web-browser application so students and chemical-biology researchers can quickly visualize receptor/ligand complexes and their unique binding interactions.
BINding ANAlyzer (BINANA) 是一种用于识别和描述受体/配体相互作用以及其他有助于结合的因素的算法。我们最近对 BINANA 进行了更新,使其更容易被更广泛的受众使用。我们还将 Python3 代码库移植到了 JavaScript 中,从而使 BINANA 分析能够在网络浏览器中进行。作为原理验证,我们创建了一个网络浏览器应用程序,使学生和化学生物学研究人员能够快速可视化受体/配体复合物及其独特的结合相互作用。