Sonune Swapnil P, Gaur Anil K, Shenoy Anuradha
Physical Medicine and Rehabilitation, All India Institute of Physical Medicine and Rehabilitation, Mumbai, Maharashtra, India.
J Family Med Prim Care. 2021 Nov;10(11):4205-4211. doi: 10.4103/jfmpc.jfmpc_70_21. Epub 2021 Nov 29.
Study the correlation of depression and quality of life (QoL) in primary caregivers (mothers) of children with cerebral palsy (CP).
An observational cross-sectional study was conducted on a total of 203 primary caregivers (mothers) of children with CP. The depression and QoL in the caregivers were assessed using the Montgomery and Asberg Depression Rating Scale and World Health Organization Quality of Life Instrument (WHOQOL-BREF) (physical, psychological, social and environmental domains), respectively. The child's gross motor function level was determined using the Gross Motor Functional Classification System-Expanded and Revised (GMFCS-ER). The association of depression and QoL in mothers to functional limitation in children were assessed. For statistical methods, < 0.05 was considered significant.
The severity of the depression showed a statistically significant negative correlation with the physical domain ( = -0.498, < 0.0001), psychological domains ( = -0.486, < 0.0001), social relationships ( = -0.165, = 0.019) and environmental domains ( = -0.195, = 0.005). The mean QoL domains scores showed a decreasing trend with increasing motor dysfunction of the child, with a statistical association for physical ( = -0.327, < 0.0001) and psychological domains ( = -0.440, < 0.0001). Out of all the baseline demographic factors, the child's age was a significant risk factor affecting the mother's QoL ( = 0.041).
CP, being a debilitating disease, requires around-the-clock caregiving for the child. However, caregiving causes a significant impact on the QoL with increasing severity of depression among the mothers.
研究脑瘫（CP）患儿的主要照料者（母亲）的抑郁状况与生活质量（QoL）之间的相关性。
对总共203名CP患儿的主要照料者（母亲）进行了一项观察性横断面研究。分别使用蒙哥马利和阿斯伯格抑郁评定量表以及世界卫生组织生活质量量表（WHOQOL - BREF）（身体、心理、社会和环境领域）对照料者的抑郁状况和生活质量进行评估。使用粗大运动功能分类系统扩展和修订版（GMFCS - ER）确定患儿的粗大运动功能水平。评估母亲的抑郁状况和生活质量与患儿功能受限之间的关联。对于统计方法，P < 0.05被认为具有统计学意义。
抑郁严重程度与身体领域（r = -0.498，P < 0.0001）、心理领域（r = -0.486，P < 0.0001）、社会关系（r = -0.165，P = 0.019）和环境领域（r = -0.195，P = 0.005）呈统计学显著负相关。生活质量领域的平均得分随着患儿运动功能障碍的增加呈下降趋势，在身体领域（r = -0.327，P < 0.0001）和心理领域（r = -0.440，P < 0.0001）具有统计学关联。在所有基线人口统计学因素中，患儿年龄是影响母亲生活质量的一个显著危险因素（P = 0.041）。
CP作为一种使人衰弱的疾病，需要对患儿进行全天候照料。然而，照料对生活质量有显著影响，母亲的抑郁严重程度也随之增加。
