不同生理和病理条件下大鼠棕色脂肪组织的体内葡萄糖利用及胰岛素敏感性
Glucose utilization in vivo and insulin-sensitivity of rat brown adipose tissue in various physiological and pathological conditions.
作者信息
Ferré P, Burnol A F, Leturque A, Terretaz J, Penicaud L, Jeanrenaud B, Girard J
出版信息
Biochem J. 1986 Jan 1;233(1):249-52. doi: 10.1042/bj2330249.
Abstract
Brown-adipose-tissue glucose utilization rate and its insulin-sensitivity were measured in vivo in the anaesthetized rat by a 2-deoxy[1-3H]glucose technique. Glucose utilization can be increased 60-fold by insulin, to reach extremely high rates. Glucose utilization and its insulin-sensitivity are modulated in accordance with physiological or pathological conditions.
摘要
采用2-脱氧[1-³H]葡萄糖技术，在麻醉大鼠体内测量棕色脂肪组织的葡萄糖利用率及其胰岛素敏感性。胰岛素可使葡萄糖利用率提高60倍，达到极高水平。葡萄糖利用率及其胰岛素敏感性会根据生理或病理状况进行调节。
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