• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

A Natural Novel Mutation in the Promoter Reducing Carbapenems Resistance in a Clinical Escherichia coli Strain.

作者信息

Li Yiming, Zhang Rong, Wang Shaolin

机构信息

College of Veterinary Medicine, China Agricultural Universitygrid.22935.3f, Beijing, China.

The Second Affiliated Hospital of Zhejiang University, Zhejiang University, Hangzhou, China.

出版信息

Microbiol Spectr. 2022 Feb 23;10(1):e0118321. doi: 10.1128/spectrum.01183-21. Epub 2022 Feb 9.

DOI:10.1128/spectrum.01183-21
PMID:35138141
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8826935/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4330/8826935/125ce6276e37/spectrum.01183-21-f001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4330/8826935/125ce6276e37/spectrum.01183-21-f001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4330/8826935/125ce6276e37/spectrum.01183-21-f001.jpg

相似文献

1
A Natural Novel Mutation in the Promoter Reducing Carbapenems Resistance in a Clinical Escherichia coli Strain.临床大肠埃希菌菌株启动子区域的一种新型自然突变降低了对碳青霉烯类药物的耐药性
Microbiol Spectr. 2022 Feb 23;10(1):e0118321. doi: 10.1128/spectrum.01183-21. Epub 2022 Feb 9.
2
Antibiotic exposure elicits the emergence of colistin- and carbapenem-resistant Escherichia coli coharboring MCR-1 and NDM-5 in a patient.抗生素暴露致使一名患者体内出现同时携带MCR-1和NDM-5的耐黏菌素和耐碳青霉烯类大肠杆菌。
Virulence. 2018;9(1):1001-1007. doi: 10.1080/21505594.2018.1486140.
3
Coexistence of MCR-1 and NDM-9 in a clinical carbapenem-resistant Escherichia coli isolate.临床分离的耐碳青霉烯类大肠杆菌中MCR-1和NDM-9的共存
Int J Antimicrob Agents. 2017 Apr;49(4):517-518. doi: 10.1016/j.ijantimicag.2017.02.001. Epub 2017 Feb 17.
4
Biochemical analysis of metallo-β-lactamase NDM-3 from a multidrug-resistant Escherichia coli strain isolated in Japan.对从日本分离出的一株耐多药大肠杆菌中金属β-内酰胺酶NDM-3的生化分析。
Antimicrob Agents Chemother. 2014 Jun;58(6):3538-40. doi: 10.1128/AAC.02793-13. Epub 2014 Mar 31.
5
Coexistence of Two Genes on an IncF Plasmid as Revealed by Nanopore Sequencing.纳米孔测序揭示 IncF 质粒上两个基因的共存。
Antimicrob Agents Chemother. 2018 Apr 26;62(5). doi: 10.1128/AAC.00110-18. Print 2018 May.
6
Novel variant NDM-11 and other NDM-1 variants in multidrug-resistant Escherichia coli from South India.来自印度南部的多重耐药大肠杆菌中新型 NDM-11 和其他 NDM-1 变体。
J Glob Antimicrob Resist. 2018 Sep;14:154-157. doi: 10.1016/j.jgar.2018.04.001. Epub 2018 Apr 12.
7
Emergence of a multidrug-resistant clinical isolate of Escherichia coli ST8499 strain producing NDM-13 carbapenemase in the Republic of Korea.韩国出现一株携带 NDM-13 碳青霉烯酶的多重耐药临床分离大肠杆菌 ST8499 菌株。
Diagn Microbiol Infect Dis. 2019 Aug;94(4):410-412. doi: 10.1016/j.diagmicrobio.2019.02.013. Epub 2019 Feb 21.
8
Detection of carbapenem-resistant Escherichia coli and Klebsiella pneumoniae producing NDM-1 in Lebanon.黎巴嫩产NDM-1的耐碳青霉烯类大肠杆菌和肺炎克雷伯菌的检测。
J Infect Dev Ctries. 2012 May 14;6(5):457-61. doi: 10.3855/jidc.2340.
9
Colistin- and Carbapenem-Resistant Escherichia coli Harboring mcr-1 and blaNDM-5, Causing a Complicated Urinary Tract Infection in a Patient from the United States.携带mcr-1和blaNDM-5基因的耐黏菌素和耐碳青霉烯类大肠杆菌,导致一名美国患者发生复杂性尿路感染
mBio. 2016 Aug 30;7(4):e01191-16. doi: 10.1128/mBio.01191-16.
10
NDM-12, a novel New Delhi metallo-β-lactamase variant from a carbapenem-resistant Escherichia coli clinical isolate in Nepal.NDM-12,一种来自尼泊尔一株耐碳青霉烯类大肠杆菌临床分离株的新型新德里金属β-内酰胺酶变体。
Antimicrob Agents Chemother. 2014 Oct;58(10):6302-5. doi: 10.1128/AAC.03355-14. Epub 2014 Aug 4.

引用本文的文献

1
Highly Conserved Genetic Factors Regulating Gene Expression.调控基因表达的高度保守遗传因子
J Microbiol Biotechnol. 2025 Jul 14;35:e2412081. doi: 10.4014/jmb.2412.12081.
2
From genomics to treatment: overcoming pan-drug-resistant in clinical settings.从基因组学到治疗:克服临床环境中的泛耐药性
Front Pharmacol. 2025 May 30;16:1570278. doi: 10.3389/fphar.2025.1570278. eCollection 2025.

本文引用的文献

1
Exploring the Role of L10 Loop in New Delhi Metallo-β-lactamase (NDM-1): Kinetic and Dynamic Studies.探讨 L10 环在新德里金属β-内酰胺酶(NDM-1)中的作用:动力学和动态研究。
Molecules. 2021 Sep 9;26(18):5489. doi: 10.3390/molecules26185489.
2
Emerging Carriage of NDM-5 and MCR-1 in From Healthy People in Multiple Regions in China: A Cross Sectional Observational Study.中国多个地区健康人群中NDM-5和MCR-1的新出现携带情况:一项横断面观察性研究
EClinicalMedicine. 2018 Dec 4;6:11-20. doi: 10.1016/j.eclinm.2018.11.003. eCollection 2018 Dec.
3
NDM Metallo-β-Lactamases and Their Bacterial Producers in Health Care Settings.
在医疗环境中 NDM 型金属β-内酰胺酶及其细菌生产者
Clin Microbiol Rev. 2019 Jan 30;32(2). doi: 10.1128/CMR.00115-18. Print 2019 Mar 20.
4
Role of non-active site residues in maintaining New Delhi metallo-β-lactamase-1(NDM-1) function: an approach of site-directed mutagenesis and docking.非活性位点残基在维持新德里金属β-内酰胺酶-1(NDM-1)功能中的作用:定点诱变与对接方法
FEMS Microbiol Lett. 2021 Mar 30;368(4). doi: 10.1093/femsle/fnz003.
5
Ten Years with New Delhi Metallo-β-lactamase-1 (NDM-1): From Structural Insights to Inhibitor Design.与新德里金属β-内酰胺酶-1(NDM-1)共处的十年:从结构洞察到抑制剂设计
ACS Infect Dis. 2019 Jan 11;5(1):9-34. doi: 10.1021/acsinfecdis.8b00247. Epub 2018 Nov 28.
6
blaNDM-21, a new variant of blaNDM in an Escherichia coli clinical isolate carrying blaCTX-M-55 and rmtB.blaNDM-21,一株携带 blaCTX-M-55 和 rmtB 的大肠杆菌临床分离株中的 blaNDM 的新变体。
J Antimicrob Chemother. 2018 Sep 1;73(9):2336-2339. doi: 10.1093/jac/dky226.
7
Molecular and computational approaches to understand resistance of New Delhi metallo β-lactamase variants (NDM-1, NDM-4, NDM-5, NDM-6, NDM-7)-producing strains against carbapenems.采用分子和计算方法了解产生新德里金属β-内酰胺酶变体(NDM-1、NDM-4、NDM-5、NDM-6、NDM-7)的菌株对碳青霉烯类抗生素耐药的机制。
J Biomol Struct Dyn. 2019 May;37(8):2061-2071. doi: 10.1080/07391102.2018.1475261. Epub 2018 Dec 5.
8
Unicycler: Resolving bacterial genome assemblies from short and long sequencing reads.单轮循环器:从短读长和长读长测序数据中解析细菌基因组组装结果
PLoS Comput Biol. 2017 Jun 8;13(6):e1005595. doi: 10.1371/journal.pcbi.1005595. eCollection 2017 Jun.
9
Comprehensive resistome analysis reveals the prevalence of NDM and MCR-1 in Chinese poultry production.综合抗性组分析揭示了 NDM 和 MCR-1 在中国家禽生产中的流行情况。
Nat Microbiol. 2017 Feb 6;2:16260. doi: 10.1038/nmicrobiol.2016.260.
10
Genomic Characteristics of NDM-Producing Enterobacteriaceae Isolates in Australia and Their blaNDM Genetic Contexts.澳大利亚产NDM的肠杆菌科分离株的基因组特征及其blaNDM基因背景
Antimicrob Agents Chemother. 2015 Oct 19;60(1):136-41. doi: 10.1128/AAC.01243-15. Print 2016 Jan.