新型隐球菌临床分离株的蛋白水解活性。
Proteolytic activity of a clinical isolate of Cryptococcus neoformans.
作者信息
Brueske C H
出版信息
J Clin Microbiol. 1986 Mar;23(3):631-3. doi: 10.1128/jcm.23.3.631-633.1986.
Abstract
A clinical isolate of Cryptococcus neoformans was grown on essential salts medium without (NH4)2SO4 and supplemented with bovine serum albumin as the sole carbon and nitrogen source. Growth on this medium resulted in secretion of proteolytic enzymes by the organism. The secretion of protease enzymes was inhibited by (NH4)2SO4 and glucose. Proteolytic activity may be a factor in virulence and pathogenicity of C. neoformans.
摘要
新型隐球菌的一株临床分离株在不含硫酸铵且添加牛血清白蛋白作为唯一碳源和氮源的基本盐培养基上生长。该菌株在这种培养基上生长会分泌蛋白水解酶。蛋白酶的分泌受到硫酸铵和葡萄糖的抑制。蛋白水解活性可能是新型隐球菌毒力和致病性的一个因素。
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