ENT institute and Department of Otorhinolaryngology, Eye & ENT Hospital, Fudan University, Shanghai, China.
NHC Key Laboratory of Hearing Medicine (Fudan University), Shanghai, China.
Methods Mol Biol. 2022;2438:251-275. doi: 10.1007/978-1-0716-2035-9_16.
Hair cells in cochlea and vestibular organs depend on the coordinated cell polarity to perform the normal auditory or balance function. The mouse inner ear is one of the ideal model to study planar cell polarity. In this chapter, we introduce a series of general experimental methods for studying planar cell polarity in the inner ear. The approaches presented here are also applicable to other organs with particular polarity phenotypes.
耳蜗和前庭器官中的毛细胞依赖于细胞极性的协调来发挥正常的听觉或平衡功能。小鼠内耳是研究平面细胞极性的理想模型之一。在本章中，我们介绍了一系列用于研究内耳平面细胞极性的一般实验方法。这里介绍的方法也适用于具有特定极性表型的其他器官。
