School of Public Health, College of Health Science and Medicine, Dilla University, Dilla, Ethiopia.
Department of Nursing, College of Health Science and Medicine, Dilla University, Dilla, Ethiopia.
Hum Vaccin Immunother. 2022 Dec 31;18(1):2035558. doi: 10.1080/21645515.2022.2035558. Epub 2022 Feb 11.
In Ethiopia, measles continues to be the cause of a significant number of vaccine-preventable infant morbidity and mortality due to the low vaccination rate. However, understanding the geographical distribution of the measles-containing vaccine first dose (MCV1) and identifying associated factors is crucial to setting up appropriate interventions. This study aimed to explore the spatial distribution and associated factors of MCV1 coverage among children aged 12-23 months in Ethiopia using national representative data.
A cross-sectional study design using a two-stage stratified sampling technique was used. The analysis was performed using STATA 14.2, ArcGIS 10.8, and SaTScan version 9.6 software. To find significant related factors with measles vaccination, researchers used multilevel logistic regression.
The prevalence of MCV1 in Ethiopia was 58.5%. A spatial variation of MCV1 coverage was observed across the study area. The most likely significant primary clusters with low MCV1 coverage were observed in Liben, Afder, Shebelle, Korahe, and Nogob zones of the Somali region; Bale and Guji zones of the Oromia region, and Gedeo and Sidama zones of the SNNPR. Rural areas, maternal primary education, secondary and above school education, Orthodox religion, Muslim religion, health facility delivery, and Afar region were significantly associated with MCV1 vaccination.
The overall MCV1 coverage in Ethiopia was low. Aside from the inadequate coverage, there was a geographical variation across the country. Low MCV1 coverage areas should be prioritized to improve vaccination efforts to control measles across the country.
在埃塞俄比亚,由于疫苗接种率低,麻疹仍然是导致大量婴儿发病和死亡的可预防疾病。然而,了解含麻疹成分疫苗(MCV1)的地理分布并确定相关因素对于制定适当的干预措施至关重要。本研究旨在利用全国代表性数据探讨埃塞俄比亚 12-23 月龄儿童 MCV1 覆盖率的空间分布及相关因素。
本研究采用两阶段分层抽样技术进行横断面研究。使用 STATA 14.2、ArcGIS 10.8 和 SaTScan 版本 9.6 软件进行分析。为了找到与麻疹疫苗接种相关的显著因素,研究人员使用多水平逻辑回归进行分析。
埃塞俄比亚 MCV1 的流行率为 58.5%。在整个研究区域观察到 MCV1 覆盖率的空间变化。在索马里地区的利本、阿德尔、谢贝利、科拉和诺格博地区;奥罗米亚地区的巴莱和古吉地区;以及南方各族州的盖多和锡达马地区,发现了具有低 MCV1 覆盖率的最可能显著原发性聚集。农村地区、母亲小学教育、中学及以上教育、东正教、伊斯兰教、医疗设施分娩以及阿法尔地区与 MCV1 疫苗接种显著相关。
埃塞俄比亚的总体 MCV1 覆盖率较低。除了覆盖率不足外,该国还存在地域差异。应优先考虑低 MCV1 覆盖率地区,以加强疫苗接种工作,在全国范围内控制麻疹。