Department of Neurology, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
School of Medicine, Welkite University, Wolkite, Ethiopia.
J Med Case Rep. 2022 Feb 12;16(1):56. doi: 10.1186/s13256-022-03264-3.
Cerebral venous thrombosis is a rare form of venous stroke with diverse clinical manifestations. Word-finding difficulty (anomia) is rarely reported in patients with cerebral venous thrombosis.
We report a 30-year-old right-handed Ethiopian female patient, who presented with global headache associated with a new onset word-finding difficulty of 2 weeks duration. The headache was not responsive to over-the-counter medications. She reported blurring of vision and nausea. Two months previously, she gave birth to a dead fetus. On neurological assessment, the patient was fully conscious and oriented, with a Glasgow coma score of 15/15, and cranial nerves, motor, and sensory examinations were unremarkable. Examination of fundus showed grade 2 papilledema bilaterally. Language assessment showed normal fluency, compression, naming, reading, and repetition. Naming was assessed using a 60 second word generating test, which indicated anomia. Brain magnetic resonance imaging showed left temporoparietal ischemia, magnetic resonance venography showed thrombosis of the left transverse, sigmoid sinus, and corresponding cortical veins. She was started on warfarin 5 mg daily for 6 months and showed significant resolution of symptoms, including the anomia.
The present case describes a young female patient with reversible anomia as a complication of cerebral venous thrombosis. The case also highlights the importance of timely diagnosis and treatment of cerebral venous thrombosis for a benign prognosis.
脑静脉血栓形成是一种罕见的静脉性卒中,临床表现多样。脑静脉血栓形成患者很少出现找词困难(命名障碍)。
我们报告了一位 30 岁的右利手埃塞俄比亚女性患者,以全头痛起病,伴有新发的找词困难,病程持续 2 周。头痛对非处方药物无反应。她还诉有视力模糊和恶心。2 个月前,她生下死胎。神经科评估时,患者意识清醒,定向力正常,格拉斯哥昏迷评分 15/15,颅神经、运动和感觉检查均无异常。眼底检查双侧 2 级视盘水肿。语言评估显示流利度、压缩、命名、阅读和重复正常。命名通过 60 秒单词生成测试进行评估,结果提示命名障碍。脑磁共振成像显示左颞顶叶缺血,磁共振静脉造影显示左侧横窦、乙状窦和相应的皮质静脉血栓形成。她开始每天服用华法林 5mg,治疗 6 个月后症状明显缓解,包括命名障碍。
本病例描述了一位年轻女性患者,其脑静脉血栓形成的并发症为可逆性命名障碍。该病例还强调了及时诊断和治疗脑静脉血栓形成以获得良好预后的重要性。