Liu Liu, Wei Yan, Teng Yue, Yan Juntao, Li Fuming, Chen Yingyao
School of Public Health, Fudan University, Shanghai, People's Republic of China.
NHC Key Laboratory of Health Technology Assessment, Fudan University, Shanghai, People's Republic of China.
Patient Prefer Adherence. 2022 Feb 4;16:297-306. doi: 10.2147/PPA.S344622. eCollection 2022.
To assess health-related quality of life (HRQoL) and utility scores of lung cancer patients treated with traditional Chinese medicine (TCM) in China.
This cross-sectional study included lung cancer patients treated with TCM in seven tertiary hospitals in Shanghai, China. The HRQoL and utility scores of these patients were measured using the five-level EQ-5D (EQ-5D-5L). The EQ-5D-5L utility scores were derived from the Chinese EQ-5D-5L Value Set. The relationships between HRQoL and the socio-demographic and clinical characteristics of these patients were further explored by Tobit regression.
This study included a total of 347 patients. Their mean ± SD and median EQ-5D-5L utility scores were 0.851 ± 0.198 and 0.893, respectively. The highest proportion of participants reporting problems was observed in pain/discomfort dimension (57.9%) and anxiety/depression (45.5%). Lung cancer patients treated with TCM had poor HRQoL, influenced by cancer clinical stage.
Lung cancer patients treated with TCM have poor HRQoL, with many patients reporting problems in the pain/discomfort and anxiety/depression dimensions. The information on health utility scores and HRQoL of lung cancer patients treated with TCM could be useful for future supportive care, economic evaluations and decision-making in China.
评估在中国接受中医治疗的肺癌患者的健康相关生活质量（HRQoL）和效用得分。
这项横断面研究纳入了在中国上海七家三级医院接受中医治疗的肺癌患者。使用五级EQ-5D（EQ-5D-5L）对这些患者的HRQoL和效用得分进行测量。EQ-5D-5L效用得分源自中国EQ-5D-5L价值集。通过Tobit回归进一步探讨HRQoL与这些患者的社会人口统计学和临床特征之间的关系。
本研究共纳入347例患者。他们的平均±标准差和中位数EQ-5D-5L效用得分分别为0.851±0.198和0.893。在疼痛/不适维度（57.9%）和焦虑/抑郁（45.5%）中观察到报告问题的参与者比例最高。接受中医治疗的肺癌患者HRQoL较差，受癌症临床分期影响。
接受中医治疗的肺癌患者HRQoL较差，许多患者在疼痛/不适和焦虑/抑郁维度报告有问题。中医治疗肺癌患者的健康效用得分和HRQoL信息可能对中国未来的支持性护理、经济评估和决策有用。
