Department of Pediatric Dentistry, Faculty of Dentistry, Chulalongkorn University, 34 Henri-Dunant Road, Wangmai, Pathumwan, Bangkok, 10330, Thailand.
Clin Oral Investig. 2022 Jun;26(6):4437-4445. doi: 10.1007/s00784-022-04407-y. Epub 2022 Feb 21.
To evaluate the remineralization of artificial interproximal enamel caries (AIEC) adjacent to alkasite, high viscous glass ionomer cement (HVGIC), and resin composite in class II restorations.
Human enamel specimens were randomly assigned to 3 groups (n = 22): Filtek™ Z350, EQUIA Forte, and Cention N. The baseline hardness was determined using a Knoop microhardness assay. AIEC was formed in the specimens, and they were placed in contact with the proximal restorative materials then subjected to a 7-day pH cycling. Microhardness was determined post-artificial caries formation and post-pH cycling. The differences in the percentage of surface hardness recovery (%SHR) between the groups were compared using the Kruskal-Wallis test. The Dunn's test was used for between-group comparisons (p < 0.05). Specimen surface morphology was evaluated using scanning electron microscopy (SEM), and the calcium, phosphorus, and fluoride contents were analyzed by energy-dispersive spectroscopy (EDS). ANOVA with the post hoc Tukey multiple comparison test was used to evaluate the differences between groups (p < 0.05).
The Cention N %SHR was the highest, followed by EQUIA Forte, and Filtek™ Z350. There was a significant difference in the %SHR between Cention N and Filtek™ Z350 (p < 0.05). In contrast, there were no significant difference between Cention N and EQUIA Forte. Significantly increased enamel surface fluoride content was observed in the Cention N compared with Filtek™ Z350 specimens (p < 0.05). The SEM image of the Cention N specimens demonstrated the greatest mineral deposition.
Cention N markedly increased the surface hardness and fluoride content of adjacent AIEC compared with Filtek™ Z350 restorations.
Cention N is a promising alternative restorative material to remineralize initial enamel lesions in approximal adjacent surfaces, especially in high-risk caries patients.
评估人工邻面釉质龋(AIEC)旁的再矿化效果,邻面接触区修复材料包括 alkasite、高粘性玻璃离子水门汀(HVGIC)和树脂复合材料。
将人釉质标本随机分为 3 组(n=22):Filtek™ Z350、EQUIA Forte 和 Cention N。使用 Knoop 显微硬度仪测定基线硬度。在标本中形成 AIEC,使它们与近中修复材料接触,然后进行为期 7 天的 pH 循环。在人工龋形成后和 pH 循环后测定显微硬度。使用 Kruskal-Wallis 检验比较各组之间表面硬度恢复百分比(%SHR)的差异。使用 Dunn 检验进行组间比较(p<0.05)。使用扫描电子显微镜(SEM)评估标本表面形态,通过能谱分析(EDS)分析钙、磷和氟含量。使用方差分析和事后 Tukey 多重比较检验比较组间差异(p<0.05)。
Cention N 的 %SHR 最高,其次是 EQUIA Forte 和 Filtek™ Z350。Cention N 和 Filtek™ Z350 之间的 %SHR 有显著差异(p<0.05)。相比之下,Cention N 和 EQUIA Forte 之间没有显著差异。与 Filtek™ Z350 标本相比,Cention N 标本的釉质表面氟含量显著增加(p<0.05)。Cention N 标本的 SEM 图像显示出最大的矿物质沉积。
与 Filtek™ Z350 修复体相比,Cention N 显著增加了 AIEC 邻面的表面硬度和氟含量。
Cention N 是一种有前途的替代修复材料,可再矿化近中邻面的初始釉质病变,尤其是在高龋风险患者中。