Di Lauro Alessandro, Di Duca Fabiana, Montuori Paolo, Dal Piva Amanda Maria de Oliveira, Tribst João Paulo Mendes, Borges Alexandre Luiz Souto, Ausiello Pietro
Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples Federico II, Via S. Pansini 5, 80131 Naples, Italy.
Department of Public Health, University of Naples Federico II, Via Sergio Pansini 5, 80131 Naples, Italy.
J Funct Biomater. 2023 Feb 15;14(2):109. doi: 10.3390/jfb14020109.
This study evaluated the effect of pH and temperature on the ion (F and Ca) release of a resin-based material containing alkaline fillers and a self-setting high-viscous glass ionomer cement. Disks were prepared according to manufacturers' instructions for both materials: the EF group (Equia Forte HT filling, GC) and the CN group (, Ivoclar). Specimens were immersed in 50 mL buffer solution with three different pHs (4.8, 6.8, and 8.8), and stored at 0°, 18°, 37°, and 44 °C. After 24 h, 7 d, and 28 d, cumulative F and Ca releases were analyzed by chromatography and mass spectrometry, and pH was measured. Both materials showed minimal changes in pH with final values after 28 d of 5.17 ± 0.56 for CN and 5.12 ± 0.24 for EF. In all experimental conditions, the percentages of ion release were higher for EF than for CF. In particular, both materials showed a significant difference in temperature in F release. Regardless of the pH values, the highest Ca ion release was after 28 days, with a significant difference in temperature for CN and EF. Within the limit of this study, the temperature storage influenced ion release and the high-viscous glass ionomer showed the maximum values.
本研究评估了pH值和温度对含碱性填料的树脂基材料及自凝高粘性玻璃离子水门汀离子（氟和钙）释放的影响。按照两种材料制造商的说明制备圆盘：EF组（Equia Forte HT充填材料，GC公司）和CN组（Ivoclar公司）。将样本浸入50 mL具有三种不同pH值（4.8、6.8和8.8）的缓冲溶液中，并分别储存在0℃、18℃、37℃和44℃环境下。在24小时、7天和28天后，通过色谱法和质谱法分析氟和钙的累积释放量，并测量pH值。两种材料的pH值变化均极小，CN组28天后的最终值为5.17±0.56，EF组为5.12±0.24。在所有实验条件下，EF组的离子释放百分比均高于CF组。特别是，两种材料在氟释放方面的温度差异显著。无论pH值如何，钙的最高离子释放在28天后出现，CN组和EF组在温度方面存在显著差异。在本研究范围内，储存温度影响离子释放，且高粘性玻璃离子水门汀呈现出最大值。
