Borneo Marine Research Institute, Universiti Malaysia Sabah, Kota Kinabalu 88400, Sabah, Malaysia.
Faculty of Pharmacy and Health Sciences, University Kuala Lumpur Royal College of Medicine Perak, Ipoh 30450, Perak, Malaysia.
Mar Drugs. 2022 Jan 25;20(2):101. doi: 10.3390/md20020101.
Malaysia has a long coastline surrounded by various islands, including North Borneo, that provide a suitable environment for the growth of diverse species of seaweeds. Some of the important North Bornean seaweed species are , , (Rhodophyta), , (Chlorophyta), and (Ochrophyta). This review aims to highlight the therapeutic potential of North Bornean seaweeds and their nutraceutical profiling. North Bornean seaweeds have demonstrated anti-inflammatory, antioxidant, antimicrobial, anticancer, cardiovascular protective, neuroprotective, renal protective and hepatic protective potentials. The protective roles of the seaweeds might be due to the presence of a wide variety of nutraceuticals, including phthalic anhydride, 3,4-ethylenedioxythiophene, 2-pentylthiophene, furoic acid (), eicosapentaenoic acid, palmitoleic acid, fucoxanthin, β-carotene (), eucalyptol, oleic acid, dodecanal, pentadecane (), canthaxanthin, oleic acid, pentadecanoic acid, eicosane (), pseudoephedrine, palmitic acid, monocaprin (), dictyohydroperoxide, squalene, fucosterol, saringosterol (), and lutein, neophytadiene, cholest-4-en-3-one and -vaccenic acid (). Extensive studies on the seaweed isolates are highly recommended to understand their bioactivity and mechanisms of action, while highlighting their commercialization potential.
马来西亚拥有漫长的海岸线，周围环绕着各种岛屿，包括北婆罗洲，这些岛屿为各种海藻的生长提供了适宜的环境。北婆罗洲的一些重要海藻物种包括，（红藻门）、（绿藻门）、（褐藻门）、（红藻门）、（绿藻门）和（黄藻门）。本综述旨在强调北婆罗洲海藻的治疗潜力及其营养成分分析。北婆罗洲海藻已表现出抗炎、抗氧化、抗菌、抗癌、心血管保护、神经保护、肾保护和肝保护潜力。海藻的保护作用可能是由于存在各种营养成分，包括邻苯二甲酸酐、3,4-亚乙基二氧噻吩、2-戊基噻吩、糠酸（）、二十碳五烯酸、棕榈油酸、岩藻黄素、β-胡萝卜素（）、桉叶醇、油酸、十二醛、十五烷（）、角黄素、油酸、十五烷酸、二十烷（）、伪麻黄碱、棕榈酸、单月桂酸甘油酯（）、二氢过氧二甲酰、角鲨烯、岩藻甾醇、芝麻甾醇（）和叶黄素、新植二烯、胆甾-4-烯-3-酮和-麦角甾烯酸（）。强烈建议对海藻分离物进行广泛研究，以了解其生物活性和作用机制，同时突出其商业化潜力。
