Department of Pharmaceutical Analysis and Medicinal Chemistry, Faculty of Pharmacy, Universitas Padjadjaran, Bandung 45363, Indonesia.
Department of Pharmaceutical Biology, Faculty of Pharmacy, Universitas Padjadjaran, Bandung 45363, Indonesia.
Molecules. 2022 Feb 10;27(4):1201. doi: 10.3390/molecules27041201.
Soursop ( Lin.) is a plant belonging to the Annonaceae family that has been widely used globally as a traditional medicine for many diseases. In this review, we discuss the traditional use, chemical content, and pharmacological activities of . From 49 research articles that were obtained from 1981 to 2021, 's activities were shown to include anticancer (25%), antiulcer (17%), antidiabetic (14%), antiprotozoal (10%), antidiarrhea (8%), antibacterial (8%), antiviral (8%), antihypertensive (6%), and wound healing (4%). Several biological activities and the general mechanisms underlying the effects of have been tested both in vitro and in vivo. contains chemicals such as acetogenins (annomuricins and annonacin), alkaloids (coreximine and reticuline), flavonoids (quercetin), and vitamins, which are predicted to be responsible for the biological activity of .
刺果番荔枝（Lin.）是番荔枝科植物，在全球范围内被广泛用作传统药物，用于治疗多种疾病。在本综述中，我们讨论了刺果番荔枝的传统用途、化学成分和药理学活性。从 1981 年至 2021 年获得的 49 篇研究文章中，显示刺果番荔枝的活性包括抗癌（25%）、抗溃疡（17%）、抗糖尿病（14%）、抗原生动物（10%）、抗腹泻（8%）、抗菌（8%）、抗病毒（8%）、抗高血压（6%）和伤口愈合（4%）。已经在体外和体内测试了几种生物活性和刺果番荔枝作用的一般机制。刺果番荔枝含有化学物质，如乙酰基醇类（annonuricins 和 annonacin）、生物碱（coreximine 和 reticuline）、类黄酮（槲皮素）和维生素，这些化学物质被认为是刺果番荔枝生物活性的原因。
