Institute of Molecular Biology and Biotechnology, The University of Lahore, Lahore 54000, Pakistan.
Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Molecules. 2022 Feb 15;27(4):1300. doi: 10.3390/molecules27041300.
Engineered nanoparticles that have distinctive targeted characteristics with high potency are modernistic technological innovations. In the modern era of research, nanotechnology has assumed critical importance due to its vast applications in all fields of science. Biologically synthesized nanoparticles using plants are an alternative to conventional methods. In the present study, (bitter apple) was used for the synthesis of gold nanoparticles (AuNPs). UV-Vis's spectroscopy, XRD, SEM and FTIR were performed to confirm the formation of AuNPs. UV-Vis's spectra showed a characteristic peak at the range of 531.5-541.5 nm. XRD peaks at 2 θ = 38°, 44°, 64° and 77°, corresponding to 111, 200, 220 and 311 planes, confirmed the crystalline nature of AuNPs. Spherical AuNPs ranged mostly between 7 and 33 nm, and were measured using SEM. The FTIR analysis confirmed the presence of phytochemicals on the surface of AuNPs. Successful synthesis of AuNPs by seed extract of (bitter apple) as a capping and reducing agent represents the novelty of the present study.
采用植物合成的纳米金粒子（AuNPs）是传统方法的替代选择。在本研究中，（苦瓜）被用于合成金纳米粒子（AuNPs）。采用紫外可见分光光度计（UV-Vis）、X 射线衍射（XRD）、扫描电子显微镜（SEM）和傅里叶变换红外光谱（FTIR）等手段对 AuNPs 的形成进行了确认。紫外可见分光光度计（UV-Vis）的光谱在 531.5-541.5nm 的范围内显示出一个特征峰。XRD 的峰在 2θ=38°、44°、64°和 77°处，对应于 111、200、220 和 311 面，证实了 AuNPs 的结晶性质。SEM 测量结果表明，球形 AuNPs 的尺寸大多在 7 至 33nm 之间。FTIR 分析证实了 AuNPs 表面存在植物化学物质。本研究的新颖之处在于，成功地采用 （苦瓜）种子提取物作为 AuNPs 的稳定剂和还原剂来合成 AuNPs。
