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心血管疾病相关皮肤状况。

Cardiovascular Disease-Associated Skin Conditions.

机构信息

Dermatology Department, Universidad del Desarrollo, Facultad de Medicina Clínica Alemana, Santiago, Region Metropolitana, Chile.

Internal Medicine Department, Universidad del Desarrollo, Facultad de Medicina Clínica Alemana, Santiago, Region Metropolitana, Chile.

出版信息

Vasc Health Risk Manag. 2022 Feb 16;18:43-53. doi: 10.2147/VHRM.S343319. eCollection 2022.

DOI:10.2147/VHRM.S343319
PMID:35210782
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8859268/
Abstract

According to data from the American Heart Association and the World Health Organization, cardiovascular disease (CVD) is the most frequent cause of premature death. Several inflammatory and non-inflammatory skin diseases have been associated with metabolic syndrome and cardiovascular risk (CVR). Here, we classified these conditions into traditionally CVR-associated and those that have been linked to a lesser degree. Psoriasis and hidradenitis suppurativa are commonly associated with CVD, sharing common inflammatory pathways and a higher prevalence of traditional cardiovascular risk factors. Many other diseases could be associated indirectly - with no common pathogenic features with the atheromatous disease - but share a higher prevalence of standard cardiovascular risk and chronic inflammatory state. This review aims to highlight the associated cardiovascular risk that exists for some dermatologic diseases and sensitize cardiologists, dermatologists, and first care providers to implement risk factor control promptly.

摘要

根据美国心脏协会和世界卫生组织的数据,心血管疾病 (CVD) 是导致过早死亡的最常见原因。一些炎症性和非炎症性皮肤病与代谢综合征和心血管风险 (CVR) 有关。在这里,我们将这些疾病分为传统的与 CVR 相关的疾病和与 CVR 相关程度较低的疾病。银屑病和化脓性汗腺炎通常与 CVD 有关,它们具有共同的炎症途径和更高的传统心血管危险因素患病率。许多其他疾病可能间接相关——与动脉粥样硬化疾病没有共同的发病特征——但它们具有更高的标准心血管风险和慢性炎症状态的患病率。本综述旨在强调一些皮肤科疾病存在的相关心血管风险,并使心脏病专家、皮肤科医生和初级保健提供者意识到及时控制危险因素的重要性。

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本文引用的文献

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Risk of major adverse cardiovascular events in patients initiating biologics/apremilast for psoriatic arthritis: a nationwide cohort study.生物制剂/阿普米司特治疗银屑病关节炎患者发生主要不良心血管事件的风险:一项全国性队列研究。
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Vitiligo: The Association With Metabolic Syndrome and the Role of Simvastatin as an Immunomodulator.白癜风:与代谢综合征的关联及辛伐他汀作为免疫调节剂的作用
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Chronic Systemic Inflammatory Skin Disease as a Risk Factor for Cardiovascular Disease.慢性系统性炎症性皮肤病作为心血管疾病的一个危险因素。
Curr Probl Cardiol. 2021 May;46(5):100799. doi: 10.1016/j.cpcardiol.2021.100799. Epub 2021 Jan 24.
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Increased risk of subclinical atherosclerosis and metabolic syndrome in patients with vitiligo: a real association or a coincidence?白癜风患者亚临床动脉粥样硬化和代谢综合征风险增加:真实关联还是巧合?
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