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认识到爱泼斯坦-巴尔病毒心肌炎的罕见后遗症可导致扩张型心肌病以及伴有多瓣膜反流的急性充血性心力衰竭。

Recognizing Rare Sequelae of Epstein-Barr Virus Myocarditis Leading to Dilated Cardiomyopathy and Acute Congestive Heart Failure With Multivalvular Regurgitation.

作者信息

Aknouk Mina, Choe Suhrim, Osborn Harmony, Kanukuntla Anish, Kata Priyaranjan, Okere Arthur, Cheriyath Pramil

机构信息

Internal Medicine, Hackensack Meridian Health Ocean University Medical Center, Brick, USA.

Cardiology, Hackensack Meridian Health Ocean University Medical Center, Brick, USA.

出版信息

Cureus. 2022 Jan 22;14(1):e21504. doi: 10.7759/cureus.21504. eCollection 2022 Jan.

Abstract

Myocarditis is associated with a wide range of infections, most commonly viral (cytomegalovirus), bacterial, and parasitic (). Epstein-Barr virus (EBV) rarely causes myocarditis, which is a life-threatening complication. Autoantibodies against cardiac myocytes activate the complement system and cause diffuse myocyte necrosis. Myocarditis has a variable presentation from asymptomatic to cardiogenic shock. Over time, untreated myocarditis can progress and result in dilated ventricles. Continued dilation of ventricles leads to systolic dysfunction, conduction abnormalities, ventricular arrhythmia, heart failure, valvular abnormalities, and thromboembolism. So, we are emphasizing the importance of early diagnosis and treatment of EBV to prevent mortality. This case study represents a rare case of mortality secondary to EBV infection with resultant DCM and congestive heart failure (CHF).

摘要

心肌炎与多种感染相关,最常见的是病毒感染(巨细胞病毒)、细菌感染和寄生虫感染()。爱泼斯坦 - 巴尔病毒(EBV)很少引起心肌炎,而心肌炎是一种危及生命的并发症。针对心肌细胞的自身抗体激活补体系统并导致弥漫性心肌细胞坏死。心肌炎的表现多样,从无症状到心源性休克。随着时间推移,未经治疗的心肌炎可进展并导致心室扩张。心室持续扩张会导致收缩功能障碍、传导异常、室性心律失常、心力衰竭、瓣膜异常和血栓栓塞。因此,我们强调早期诊断和治疗EBV以预防死亡的重要性。本病例研究代表了一例罕见的因EBV感染继发扩张型心肌病(DCM)和充血性心力衰竭(CHF)而导致死亡的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b07d/8860702/0d3ccbd95794/cureus-0014-00000021504-i01.jpg

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