Ciusa G, Guida Marascia F, Virruso R, Angheben A, Guaraldi G, Cascio A
Department of Infectious Diseases, University of Modena and Reggio Emilia, Modena, Italy.
Infectious and Tropical Diseases Unit, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, Palermo, Italy.
IDCases. 2022;27:e01456. doi: 10.1016/j.idcr.2022.e01456. Epub 2022 Feb 19.
We described a case of clinical reactivation of chronic infection following CoVID-19 vaccination with BNT162b2 (Pifzer-Biontech CoVID-19 vaccine) in a 48-year old Italian man.The patient came to our attention for fever of unknown origin show a quartan pattern (every third day) associated to splenomegaly, the onset of the fever occurred one month after CoVID-19 vaccination with BNT162b2. was diagnosed using Carestart™ malaria rapid test and Polymerase-Chain Reaction. Post-vaccine transient reduction of immune reactivity is described in literature, although the mechanism is unknown.
我们描述了一名48岁意大利男子在接种BNT162b2（辉瑞-生物科技新冠疫苗）后慢性感染临床再激活的病例。该患者因不明原因发热前来就诊，发热呈间日热型（每三天一次）并伴有脾肿大，发热始于接种BNT162b2新冠疫苗后一个月。通过Carestart™疟疾快速检测和聚合酶链反应进行诊断。文献中描述了疫苗接种后免疫反应性的短暂降低，但其机制尚不清楚。
