Reneman R S, van Merode T, Hick P, Muytjens A M, Hoeks A P
Ultrasound Med Biol. 1986 Jun;12(6):465-71. doi: 10.1016/0301-5629(86)90218-8.
Changes in distensibility and cross-sectional compliance of the common carotid artery with age were studied in 80 presumed healthy volunteers, varying in age between 20 and 69 y. The distensibility was assessed from the relative increase in arterial diameter during systole normalized with respect to the arterial pulse pressure. The cross-sectional compliance was obtained by multiplying the distensibility by the arterial diameter. The relative diameter changes of the common carotid artery during the cardiac cycle were recorded on-line with a high resolution multigate pulsed Doppler system. The arterial diameter was assessed from the width of the velocity profiles which can also be recorded on-line with this system. Arterial pulse pressure was determined from brachial artery cuff blood pressure measurements. Both distensibility and cross-sectional compliance of the common carotid artery decreased linearly with age, starting in the third age decade. The reduction in the latter parameter was less pronounced, probably as a consequence of an increase in arterial diameter with age.
对80名年龄在20至69岁之间的假定健康志愿者，研究了颈总动脉的扩张性和横截面积顺应性随年龄的变化。扩张性通过收缩期动脉直径的相对增加量来评估，该增加量相对于动脉脉压进行了归一化处理。横截面积顺应性通过将扩张性乘以动脉直径获得。利用高分辨率多门脉冲多普勒系统在线记录心动周期中颈总动脉的相对直径变化。动脉直径根据速度剖面的宽度来评估，该宽度也可通过该系统在线记录。动脉脉压通过肱动脉袖带血压测量来确定。颈总动脉的扩张性和横截面积顺应性均从第三个十年开始随年龄线性下降。后一个参数的降低不太明显，可能是由于动脉直径随年龄增加所致。
