基于互联网的强迫症认知行为疗法：日本的一项多中心随机对照试验。
Guided internet-based cognitive behavioral therapy for obsessive-compulsive disorder: A multicenter randomized controlled trial in Japan.
作者信息
Matsumoto Kazuki, Hamatani Sayo, Makino Takuya, Takahashi Jumpei, Suzuki Futoshi, Ida Tomoko, Hamamura Shoko, Takiguchi Shinichiro, Tomoda Akemi, Omori Ichiro M, Kosaka Hirotaka, Shinno Seina, Ikai Tomoki, Hayashi Hiroyuki, Katayama Hiroto, Shiko Yuki, Ozawa Yoshihito, Kawasaki Yohei, Sutoh Chihiro, Shimizu Eiji
机构信息
Research Center for Child Mental Development, Chiba University, Chiba 260-8588, Japan.
Laboratory of Neuropsychology, Institute of Liberal Arts and Science, Kanazawa University, Ishikawa 920-1192, Japan.
出版信息
Internet Interv. 2022 Feb 24;28:100515. doi: 10.1016/j.invent.2022.100515. eCollection 2022 Apr.
UNLABELLED
Few studies have compared the effectiveness of internet-based cognitive behavior therapy (ICBT) for obsessive-compulsive disorder (OCD) with treatment as usual (TAU). We investigated the effectiveness of guided ICBT for patients with OCD. This prospective, randomized, controlled, assessor-blinded, multicenter clinical trial was conducted at three facilities in Japan from January 2020 to March 2021. Thirty-one patients with OCD as the primary diagnosis participated in the trial and were randomly assigned to either the intervention group or the control group. The primary outcome was the Yale-Brown obsessive-compulsive scale score; the assessors were blinded. Results of the analysis of covariance among the groups were significantly different between the groups ( < 0.01, effect size Cohen's = 1.05), indicating the superiority of guided ICBT. The results suggest that guided ICBT is more effective than TAU for treating OCD.
RCT REGISTRATION
UMIN Clinical Trials Registry (UMIN000039375).
未标注
很少有研究将基于互联网的认知行为疗法（ICBT）治疗强迫症（OCD）的效果与常规治疗（TAU）进行比较。我们调查了指导性ICBT对强迫症患者的疗效。这项前瞻性、随机、对照、评估者盲法、多中心临床试验于2020年1月至2021年3月在日本的三个机构进行。31名以强迫症为主要诊断的患者参与了试验，并被随机分配到干预组或对照组。主要结局是耶鲁-布朗强迫症量表评分；评估者是盲法的。组间协方差分析结果显示组间存在显著差异（<0.01，效应量Cohen's = 1.05），表明指导性ICBT具有优越性。结果表明，指导性ICBT在治疗强迫症方面比常规治疗更有效。
随机对照试验注册
UMIN临床试验注册中心（UMIN000039375）。
Zotero 插件