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自我指导的互联网认知行为疗法(ICBT)治疗强迫症症状:一项随机对照试验。

Self-guided internet-delivered cognitive behavior therapy (ICBT) for obsessive-compulsive symptoms: A randomized controlled trial.

机构信息

University of Technology Sydney, NSW, Australia; Macquarie University, Sydney, NSW, Australia.

Macquarie University, Sydney, NSW, Australia.

出版信息

J Anxiety Disord. 2019 Aug;66:102111. doi: 10.1016/j.janxdis.2019.102111. Epub 2019 Jul 4.

Abstract

Internet-delivered cognitive behavior therapy (ICBT) for obsessive-compulsive disorder (OCD) has been demonstrated to be efficacious across multiple clinical trials. However, most of these interventions include clinician support, and many individuals with OCD prefer to manage their own symptoms. Self-guided ICBT overcomes this problem, but to date the efficacy of self-guided interventions has only been studied in uncontrolled trials. The present study aims to examine the efficacy and acceptability of ICBT for OCD symptoms when delivered in a self-guided format using a randomized controlled trial design. In the present study, 190 participants were randomized to either a self-guided ICBT condition or a waitlist control group. 140 participants completed the baseline assessment, initiated treatment, and were included in the analyses. The between-group effect size at post-treatment was large on the self-report version of the Yale-Brown Obsessive-Compulsive Scale (d = 1.05; 95% CI 0.89-1.21). Twenty-seven percent of the ICBT condition met conservative criteria for clinically significant change at post-treatment, which increased to thirty-eight percent at three-month follow-up. Participants rated the program as highly acceptable. The results indicate that self-guided ICBT may be a viable treatment option for some individuals with OCD symptoms.

摘要

互联网认知行为疗法(ICBT)已被证明对强迫症(OCD)在多项临床试验中有效。然而,这些干预措施大多包括临床医生的支持,而许多 OCD 患者更愿意自行管理自己的症状。自我指导的 ICBT 克服了这个问题,但迄今为止,自我指导干预的疗效仅在非对照试验中进行了研究。本研究旨在通过随机对照试验设计,研究以自我指导格式提供的 OCD 症状的 ICBT 的疗效和可接受性。在本研究中,190 名参与者被随机分配到自我指导的 ICBT 条件或候补名单对照组。140 名参与者完成了基线评估、开始治疗,并纳入了分析。治疗后自我报告版本的耶鲁-布朗强迫症量表(Yale-Brown Obsessive-Compulsive Scale)的组间效应量较大(d=1.05;95%置信区间 0.89-1.21)。27%的 ICBT 条件在治疗后符合临床显著变化的保守标准,在三个月的随访中增加到 38%。参与者对该项目的评价非常高。结果表明,自我指导的 ICBT 可能是一些 OCD 症状患者的可行治疗选择。

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