Vobugari Nikitha, Raja Vikranth, Sethi Udhav, Gandhi Kejal, Raja Kishore, Surani Salim R
Department of Internal Medicine, Medstar Washington Hospital Center, Washington, DC 20010, USA.
Department of Medicine, P.S.G Institute of Medical Sciences and Research, Coimbatore 641004, Tamil Nadu, India.
Cancers (Basel). 2022 Mar 6;14(5):1349. doi: 10.3390/cancers14051349.
Well-trained machine learning (ML) and artificial intelligence (AI) systems can provide clinicians with therapeutic assistance, potentially increasing efficiency and improving efficacy. ML has demonstrated high accuracy in oncology-related diagnostic imaging, including screening mammography interpretation, colon polyp detection, glioma classification, and grading. By utilizing ML techniques, the manual steps of detecting and segmenting lesions are greatly reduced. ML-based tumor imaging analysis is independent of the experience level of evaluating physicians, and the results are expected to be more standardized and accurate. One of the biggest challenges is its generalizability worldwide. The current detection and screening methods for colon polyps and breast cancer have a vast amount of data, so they are ideal areas for studying the global standardization of artificial intelligence. Central nervous system cancers are rare and have poor prognoses based on current management standards. ML offers the prospect of unraveling undiscovered features from routinely acquired neuroimaging for improving treatment planning, prognostication, monitoring, and response assessment of CNS tumors such as gliomas. By studying AI in such rare cancer types, standard management methods may be improved by augmenting personalized/precision medicine. This review aims to provide clinicians and medical researchers with a basic understanding of how ML works and its role in oncology, especially in breast cancer, colorectal cancer, and primary and metastatic brain cancer. Understanding AI basics, current achievements, and future challenges are crucial in advancing the use of AI in oncology.
训练有素的机器学习(ML)和人工智能(AI)系统可以为临床医生提供治疗辅助,有可能提高效率并改善疗效。ML在肿瘤相关的诊断成像中已显示出高准确性,包括乳腺钼靶筛查解读、结肠息肉检测、神经胶质瘤分类和分级。通过使用ML技术,检测和分割病变的人工步骤大大减少。基于ML的肿瘤成像分析独立于评估医生的经验水平,并且结果预计会更加标准化和准确。最大的挑战之一是其在全球范围内的通用性。目前用于结肠息肉和乳腺癌的检测和筛查方法有大量数据,因此它们是研究人工智能全球标准化的理想领域。中枢神经系统癌症很罕见,根据当前的管理标准预后较差。ML为从常规获取的神经影像中揭示未发现的特征提供了前景,以改善胶质瘤等中枢神经系统肿瘤的治疗计划、预后预测、监测和反应评估。通过研究此类罕见癌症类型中的AI,可以通过增强个性化/精准医学来改进标准管理方法。本综述旨在为临床医生和医学研究人员提供对ML如何工作及其在肿瘤学中的作用的基本理解,特别是在乳腺癌、结直肠癌以及原发性和转移性脑癌方面。了解AI基础知识、当前成就和未来挑战对于推进AI在肿瘤学中的应用至关重要。