间歇性禁食与代谢健康
Intermittent Fasting and Metabolic Health.
机构信息
Department of Internal Medicine, Section of Hospital Medicine, Wake Forest University School of Medicine, Winston Salem, NC 27101, USA.
Department of Internal Medicine, Division of Gastroenterology, Wake Forest University School of Medicine, Winston Salem, NC 27101, USA.
出版信息
Nutrients. 2022 Jan 31;14(3):631. doi: 10.3390/nu14030631.
Given the ongoing strain that the obesity epidemic has placed on public health outcomes, new and effective approaches to weight control are needed. One approach to improving weight and metabolic outcomes is intermittent fasting, which consists of multiple different timing schedules for temporary food avoidance, including alternate-day fasting, other similar full-day fasting patterns, and time-restricted feeding (where the day's food is consumed over a 6-h period, allowing for 18 h of fasting). These feeding schedules have favorable metabolic effects by intermittently inducing the metabolism of fatty acids to ketones. The regimens overall lead to a decrease in weight and have been linked to improvements in dyslipidemia and blood pressure. While more research is needed on longer-term outcomes and this approach should be avoided in particular health conditions, intermittent fasting should be considered as an option for individuals who have a pattern of unhealthy weight gain using standard eating patterns.
鉴于肥胖流行给公共卫生带来的持续压力,需要新的、有效的体重控制方法。一种改善体重和代谢结果的方法是间歇性禁食,它包括多种不同的临时禁食时间安排,包括隔日禁食、其他类似的全天禁食模式和限时进食(在 6 小时内摄入一天的食物,允许 18 小时禁食)。这些喂养计划通过间歇性地诱导脂肪酸代谢为酮体,对代谢产生有利影响。这些方案总体上导致体重下降,并与血脂异常和血压改善有关。虽然还需要更多关于长期结果的研究,并且在某些特定健康状况下应避免这种方法,但对于使用标准饮食模式出现不健康体重增加的个体,应考虑间歇性禁食作为一种选择。