Department of Surgical Disciplines, All India Institute of Medical Sciences, Room No. 5026A, 5th Floor, Teaching Block, Ansari Nagar, New Delhi, 110029, India.
Department of Psychiatry, All India Institute of Medical Sciences, New Delhi, India.
Surg Endosc. 2022 Oct;36(10):7494-7502. doi: 10.1007/s00464-022-09180-3. Epub 2022 Mar 11.
There are no randomized controlled trials comparing the eTEP with IPOM repair and this randomized study was designed to compare the two techniques in terms of early pain, cost effectiveness, and quality of life.
This was a prospective randomized trial with intention to treat analysis. The primary outcome was immediate post-operative pain scores. Operative time, conversions, peri operative morbidity, hospital stay, return to daily activities, incremental cost effectiveness ratio and quality of life (WHO-QOL BREF) were secondary outcomes.
Sixty patients were randomized equally. Early post-operative pain scores and seroma rates were significantly lower and with a significantly earlier return to activity in eTEP group (p value < 0.05). With negative costs and positive effects, eTEP group was 2.4 times more cost effective.
eTEP repair is better in terms of lesser early post-operative pain, earlier return to activities and cost effectiveness in small and medium size defects.
目前尚无比较 eTEP 与 IPOM 修复的随机对照试验，本随机研究旨在比较两种技术在早期疼痛、成本效益和生活质量方面的差异。
这是一项前瞻性随机临床试验，意向治疗分析。主要结局指标为即刻术后疼痛评分。次要结局指标包括手术时间、中转率、围手术期并发症、住院时间、恢复日常活动时间、增量成本效益比和生活质量（WHO-QOL BREF）。
共有 60 例患者被随机等分为两组。eTEP 组的术后早期疼痛评分和血清肿发生率显著较低，且活动恢复时间更早（p 值均<0.05）。eTEP 组的成本为负，效果为正，增量成本效益比为 2.4 倍。
在小型和中型缺损中，eTEP 修复在术后早期疼痛较轻、活动恢复更早和成本效益方面更具优势。
