Abdulhaq Ahmed A, Hershan Almonther A, Karunamoorthi Kaliyaperumal, Al-Mekhlafi Hesham M
Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, Jazan University, Jazan, Kingdom of Saudi Arabia.
Deanship of Scientific Research, Jazan University, Jazan, Kingdom of Saudi Arabia.
Saudi J Biol Sci. 2022 Mar;29(3):1900-1910. doi: 10.1016/j.sjbs.2021.10.031. Epub 2021 Oct 22.
Alkhumra hemorrhagic fever (AHF) is a severe, often fatal hemorrhagic disease in humans. It is caused by Alkhumra hemorrhagic fever virus (AHFV), a newly described flavivirus first isolated in 1995 in Alkhumra district, south of Jeddah City, Saudi Arabia. It is transmitted from infected livestock animals to humans by direct contact with infected animals or by tick bites. In the recent past, the incidence of AHF has increased, with a total of 604 confirmed cases have been reported in Saudi Arabia between 1995 and 2020. Yet, no specific treatment or control strategies have been developed and implemented against this infection. Hence, the likelihood of increased prevalence or the occurrence of outbreaks is high, particularly in the absence of appropriate prevention and control strategies. This narrative review presents an overview of the current knowledge and future concerns about AHF globally.
阿勒胡姆拉出血热（AHF）是一种严重的、通常致命的人类出血性疾病。它由阿勒胡姆拉出血热病毒（AHFV）引起，AHFV是一种新发现的黄病毒，于1995年首次在沙特阿拉伯吉达市以南的阿勒胡姆拉地区分离出来。它通过直接接触受感染动物或蜱虫叮咬从受感染的家畜传播给人类。在最近，AHF的发病率有所上升，1995年至2020年间沙特阿拉伯共报告了604例确诊病例。然而，尚未针对这种感染制定和实施具体的治疗或控制策略。因此，患病率增加或爆发疫情的可能性很高，特别是在缺乏适当预防和控制策略的情况下。这篇叙述性综述概述了全球对AHF的现有知识和未来担忧。
