Luo Hui, Ge Hong
Department of Radiation Oncology, The Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, China.
Front Oncol. 2022 Feb 23;12:852791. doi: 10.3389/fonc.2022.852791. eCollection 2022.
Radiation therapy remains an important component of cancer treatment. Gene-encoded proteins were the actual executors of cellular functions. Proteomic was a novel technology that can systematically analysis protein composition and measure their levels of change, this was a high throughput method, and were the import tools in the post genomic era. In recent years, rapid progress of proteomic have been made in the study of cancer mechanism, diagnosis, and treatment. This article elaborates current advances and future directions of proteomics in the discovery of radiosensitive cancer biomarkers.
放射治疗仍然是癌症治疗的重要组成部分。基因编码蛋白是细胞功能的实际执行者。蛋白质组学是一项能够系统分析蛋白质组成并测量其变化水平的新技术，这是一种高通量方法，也是后基因组时代的重要工具。近年来，蛋白质组学在癌症机制、诊断和治疗的研究中取得了快速进展。本文阐述了蛋白质组学在放射敏感性癌症生物标志物发现方面的当前进展和未来方向。
