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Unveiling the distinctive traits of functional rye centromeres: minisatellites, retrotransposons, and R-loop formation.揭示功能型黑麦着丝粒的独特特征：微卫星、反转录转座子和 R 环形成。
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本文引用的文献

1
Gene editing and its applications in biomedicine.基因编辑及其在生物医学中的应用。
Sci China Life Sci. 2022 Apr;65(4):660-700. doi: 10.1007/s11427-021-2057-0. Epub 2022 Feb 18.
2
One-step base editing in multiple genes by direct embryo injection for pig trait improvement.通过直接胚胎注射在多个基因中进行一步碱基编辑以改善猪的性状。
Sci China Life Sci. 2022 Apr;65(4):739-752. doi: 10.1007/s11427-021-2013-8. Epub 2022 Jan 13.
3
Genome-wide CRISPR activation screen identifies candidate receptors for SARS-CoV-2 entry.全基因组 CRISPR 激活筛选鉴定出 SARS-CoV-2 进入的候选受体。
Sci China Life Sci. 2022 Apr;65(4):701-717. doi: 10.1007/s11427-021-1990-5. Epub 2021 Aug 20.
4
Targeted DNA demethylation produces heritable epialleles in rice.靶向DNA去甲基化在水稻中产生可遗传的表观等位基因。
Sci China Life Sci. 2022 Apr;65(4):753-756. doi: 10.1007/s11427-021-1974-7. Epub 2021 Aug 12.
5
Transient expression of a TaGRF4-TaGIF1 complex stimulates wheat regeneration and improves genome editing.TaGRF4-TaGIF1 复合物的瞬时表达可促进小麦再生并提高基因组编辑效率。
Sci China Life Sci. 2022 Apr;65(4):731-738. doi: 10.1007/s11427-021-1949-9. Epub 2021 Aug 16.
6
CRISPR technologies for precise epigenome editing.CRISPR 技术在精确表观基因组编辑中的应用。
Nat Cell Biol. 2021 Jan;23(1):11-22. doi: 10.1038/s41556-020-00620-7. Epub 2021 Jan 8.
7
Enhanced genome editing to ameliorate a genetic metabolic liver disease through co-delivery of adeno-associated virus receptor.通过共递送腺相关病毒受体增强基因编辑以改善遗传性代谢性肝病
Sci China Life Sci. 2022 Apr;65(4):718-730. doi: 10.1007/s11427-020-1744-6. Epub 2020 Aug 17.
8
High-throughput screening of a CRISPR/Cas9 library for functional genomics in human cells.高通量筛选 CRISPR/Cas9 文库在人类细胞中的功能基因组学研究。
Nature. 2014 May 22;509(7501):487-91. doi: 10.1038/nature13166. Epub 2014 Apr 9.
9
Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression.将 CRISPR 重新用作 RNA 引导的平台，用于基因表达的序列特异性控制。
Cell. 2013 Feb 28;152(5):1173-83. doi: 10.1016/j.cell.2013.02.022.

Gene editing: from technologies to applications in research and beyond.

作者信息

Wei Wensheng, Gao Caixia

机构信息

Biomedical Pioneering Innovation Center, Beijing Advanced Innovation Center for Genomics, Peking-Tsinghua Center for Life Sciences, Peking University Genome Editing Research Center, State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, Beijing, 100871, China.

State Key Laboratory of Plant Cell and Chromosome Engineering, Center for Genome Editing, Institute of Genetics and Developmental Biology, Innovation Academy for Seed Design, Chinese Academy of Sciences, Beijing, 100101, China.

出版信息

Sci China Life Sci. 2022 Apr;65(4):657-659. doi: 10.1007/s11427-022-2087-5. Epub 2022 Mar 10.

DOI:10.1007/s11427-022-2087-5
PMID:35290572
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8922976/
Abstract
摘要