• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

新冠病毒感染患者的嗅觉和味觉障碍:文献综述

Olfactory and Taste Disorders in Patients Suffering from Covid-19, a Review of Literature.

作者信息

Ghods Kimia, Alaee Arezoo

机构信息

Student of Dentistry, Membership of Dental Material Research Center, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.

Dept. of Oral Medicine, Membership of Dental Material Research Center, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.

出版信息

J Dent (Shiraz). 2022 Mar;23(1):1-6. doi: 10.30476/DENTJODS.2021.87800.1284.

DOI:10.30476/DENTJODS.2021.87800.1284
PMID:35291682
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8918638/
Abstract

Corona virus epidemic has caused a widespread disaster around the world. In studies, there are pieces of evidence of olfactory and taste dysfunction in patients with Covid-19. These symptoms occur independently or can be associated with other symptoms such as dry cough. The mechanism of the above-mentioned disorders and their clinical features in patients are not yet known. The rate of incidence of olfactory dysfunction in patients has been varied from 29.64% to 75.23% and the rate of incidence of taste dysfunction among the people can be different from 20.46% to 68.95%. Therefore, clinicians including ENT specialists and dentists should pay attention to the symptoms of anosmia and ageusia in these patients to prevent delayed diagnosis and inappropriate treatments. In this review article, data have been collected by searching the available articles in the domestic and foreign journals using databases such as PubMed, PubMed Central, Medline, EBSCO, Google Scholar, and Embase with key words of Anosmia, Ageusia, Dysgeusia, Covid-19, and Coronavirus from 2019 to 2020. Among the relevant references, 38 authoritative articles were chosen. The data showed that it seems olfactory and taste function disorders are the obvious symptoms of Covid-19, which can occur independently or with other symptoms, but the pathogenesis is not well specified yet. Therefore, further studies are required to achieve a reliable result in this area.

摘要

冠状病毒疫情在全球引发了一场广泛的灾难。在研究中,有证据表明新冠病毒肺炎患者存在嗅觉和味觉功能障碍。这些症状可单独出现,也可能与干咳等其他症状相关。上述病症在患者中的发病机制及其临床特征尚不清楚。患者嗅觉功能障碍的发生率在29.64%至75.23%之间,味觉功能障碍的发生率在20.46%至68.95%之间。因此,包括耳鼻喉科专家和牙医在内的临床医生应关注这些患者的嗅觉丧失和味觉丧失症状,以防止诊断延误和治疗不当。在这篇综述文章中,通过使用PubMed、PubMed Central、Medline、EBSCO、谷歌学术和Embase等数据库,以嗅觉丧失、味觉丧失、味觉障碍、新冠病毒肺炎和冠状病毒为关键词,搜索国内外期刊上的现有文章来收集数据。在相关参考文献中,选取了38篇权威文章。数据表明,嗅觉和味觉功能障碍似乎是新冠病毒肺炎的明显症状,可单独出现或与其他症状同时出现,但其发病机制尚未明确。因此,需要进一步研究以在该领域取得可靠结果。

相似文献

1
Olfactory and Taste Disorders in Patients Suffering from Covid-19, a Review of Literature.新冠病毒感染患者的嗅觉和味觉障碍:文献综述
J Dent (Shiraz). 2022 Mar;23(1):1-6. doi: 10.30476/DENTJODS.2021.87800.1284.
2
Sudden onset, acute loss of taste and smell in coronavirus disease 2019 (COVID-19): a systematic review.突发性、急性丧失味觉和嗅觉与 2019 年冠状病毒病(COVID-19):系统评价。
Acta Odontol Scand. 2020 Aug;78(6):467-473. doi: 10.1080/00016357.2020.1787505. Epub 2020 Aug 7.
3
The Prevalence of Olfactory and Gustatory Dysfunction in COVID-19 Patients: A Systematic Review and Meta-analysis.新冠病毒患者嗅觉和味觉功能障碍的流行情况:系统评价和荟萃分析。
Otolaryngol Head Neck Surg. 2020 Jul;163(1):3-11. doi: 10.1177/0194599820926473. Epub 2020 May 5.
4
Anosmia and dysgeusia in COVID-19: A systematic review.新型冠状病毒肺炎中的嗅觉丧失和味觉障碍:一项系统综述
Wellcome Open Res. 2020 May 13;5:94. doi: 10.12688/wellcomeopenres.15917.1. eCollection 2020.
5
A review of smell and taste dysfunction in COVID-19 patients.新冠病毒感染患者嗅觉和味觉功能障碍综述。
Med J Malaysia. 2020 Sep;75(5):574-581.
6
Olfactory and Gustatory Dysfunction in 2019 Novel Coronavirus: An Updated Systematic Review and Meta-analysis.2019新型冠状病毒所致嗅觉和味觉功能障碍:一项更新的系统评价与荟萃分析
Int J Prev Med. 2021 Dec 14;12:170. doi: 10.4103/ijpvm.IJPVM_484_20. eCollection 2021.
7
Dysgeusia: A review in the context of COVID-19.味觉障碍:COVID-19 背景下的综述。
J Am Dent Assoc. 2022 Mar;153(3):251-264. doi: 10.1016/j.adaj.2021.08.009. Epub 2021 Nov 17.
8
Loss of Smell and Taste in Patients With Suspected COVID-19: Analyses of Patients' Reports on Social Media.嗅觉和味觉丧失的疑似 COVID-19 患者:社交媒体上患者报告的分析。
J Med Internet Res. 2021 Apr 22;23(4):e26459. doi: 10.2196/26459.
9
Prevalence of olfactory and taste dysfunction in COVID-19 patients: a community care facility study.新冠病毒患者嗅觉和味觉障碍的流行情况:社区护理机构研究。
Eur Arch Otorhinolaryngol. 2021 Sep;278(9):3375-3380. doi: 10.1007/s00405-021-06647-2. Epub 2021 Feb 17.
10
[Olfactory dysfunction and COVID-19 - current state of the problem].[嗅觉功能障碍与新冠病毒病——问题现状]
Vestn Otorinolaringol. 2020;85(6):100-104. doi: 10.17116/otorino202085061100.

引用本文的文献

1
Photobiomodulation in the management of persistent olfactory and gustatory dysfunction post-COVID-19: a systematic review.光生物调节疗法在新冠后持续性嗅觉和味觉功能障碍管理中的应用:一项系统综述
Lasers Med Sci. 2025 Jun 16;40(1):283. doi: 10.1007/s10103-025-04534-4.
2
Determination of objective taste perception among Iranian medical sciences students during COVID‑19 pandemic in Yazd, Eastern Iran: a case-control pilot study.伊朗东部亚兹德 COVID-19 大流行期间医学生客观味觉感知的测定:一项病例对照初步研究。
BMC Infect Dis. 2024 Sep 18;24(1):997. doi: 10.1186/s12879-024-09897-7.
3
Anosmia and dysgeusia as markers of severity and prognosis in COVID-19.嗅觉丧失和味觉障碍作为新冠病毒病严重程度和预后的标志物
Brain Circ. 2023 Mar 24;9(1):50-51. doi: 10.4103/bc.bc_65_22. eCollection 2023 Jan-Mar.
4
Loss of Sour Taste Is the Striking Feature among Four Basic Taste Qualities in Tunisian COVID-19 Patients.味觉丧失是突尼斯新冠肺炎患者四种基本味觉中的显著特征。
J Clin Med. 2023 Jan 11;12(2):597. doi: 10.3390/jcm12020597.
5
The Prevalence and Implications of Olfactory/Gustatory Dysfunctions among Adult COVID-19 Patients: A Retrospective Cohort Multiethnic Populations Study.成年新冠病毒肺炎患者嗅觉/味觉功能障碍的患病率及其影响:一项回顾性队列多民族人群研究
Trop Med Infect Dis. 2022 Jun 23;7(7):115. doi: 10.3390/tropicalmed7070115.

本文引用的文献

1
Pathogenesis of dysgeusia in COVID-19 patients: a scoping review.新冠病毒感染患者味觉障碍的发病机制:系统评价。
Eur Rev Med Pharmacol Sci. 2021 Jan;25(2):1114-1134. doi: 10.26355/eurrev_202101_24683.
2
Coincidence of COVID-19 epidemic and olfactory dysfunction outbreak in Iran.伊朗新冠疫情与嗅觉功能障碍爆发的巧合。
Med J Islam Repub Iran. 2020 Jun 15;34:62. doi: 10.34171/mjiri.34.62. eCollection 2020.
3
Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia.SARS-CoV-2 进入基因在嗅觉系统中的非神经元表达提示了 COVID-19 相关嗅觉丧失的潜在机制。
Sci Adv. 2020 Jul 31;6(31). doi: 10.1126/sciadv.abc5801. Epub 2020 Jul 24.
4
Anosmia in COVID-19: Underlying Mechanisms and Assessment of an Olfactory Route to Brain Infection.新冠病毒感染导致的嗅觉丧失:潜在机制及经嗅觉途径感染大脑的评估
Neuroscientist. 2021 Dec;27(6):582-603. doi: 10.1177/1073858420956905. Epub 2020 Sep 11.
5
Smell and taste disorders in Spanish patients with mild COVID-19.西班牙轻症新冠肺炎患者的嗅觉和味觉障碍
Neurologia (Engl Ed). 2020 Nov-Dec;35(9):633-638. doi: 10.1016/j.nrl.2020.07.006. Epub 2020 Jul 28.
6
Impact of renal disease and comorbidities on mortality in hemodialysis patients with COVID-19: a multicenter experience from Germany.肾脏疾病及合并症对COVID-19血液透析患者死亡率的影响:来自德国的多中心经验
J Nephrol. 2020 Oct;33(5):871-874. doi: 10.1007/s40620-020-00828-8.
7
Dysgeusia in COVID-19: Possible Mechanisms and Implications.新型冠状病毒肺炎中的味觉障碍:可能的机制及影响
Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 Sep;130(3):344-346. doi: 10.1016/j.oooo.2020.06.016. Epub 2020 Jun 27.
8
Anosmia and dysgeusia in COVID-19: A systematic review.新型冠状病毒肺炎中的嗅觉丧失和味觉障碍:一项系统综述
Wellcome Open Res. 2020 May 13;5:94. doi: 10.12688/wellcomeopenres.15917.1. eCollection 2020.
9
COVID-19 and anosmia: A review based on up-to-date knowledge.新型冠状病毒肺炎与嗅觉障碍:基于最新知识的综述。
Am J Otolaryngol. 2020 Sep-Oct;41(5):102581. doi: 10.1016/j.amjoto.2020.102581. Epub 2020 Jun 2.
10
Clinical features of COVID-19 and influenza: a comparative study on Nord Franche-Comte cluster.COVID-19 和流感的临床特征:诺尔-弗朗什-孔泰集群的对比研究。
Microbes Infect. 2020 Oct;22(9):481-488. doi: 10.1016/j.micinf.2020.05.016. Epub 2020 Jun 16.