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新冠病毒感染患者的嗅觉和味觉障碍:文献综述

Olfactory and Taste Disorders in Patients Suffering from Covid-19, a Review of Literature.

作者信息

Ghods Kimia, Alaee Arezoo

机构信息

Student of Dentistry, Membership of Dental Material Research Center, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.

Dept. of Oral Medicine, Membership of Dental Material Research Center, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.

出版信息

J Dent (Shiraz). 2022 Mar;23(1):1-6. doi: 10.30476/DENTJODS.2021.87800.1284.

Abstract

Corona virus epidemic has caused a widespread disaster around the world. In studies, there are pieces of evidence of olfactory and taste dysfunction in patients with Covid-19. These symptoms occur independently or can be associated with other symptoms such as dry cough. The mechanism of the above-mentioned disorders and their clinical features in patients are not yet known. The rate of incidence of olfactory dysfunction in patients has been varied from 29.64% to 75.23% and the rate of incidence of taste dysfunction among the people can be different from 20.46% to 68.95%. Therefore, clinicians including ENT specialists and dentists should pay attention to the symptoms of anosmia and ageusia in these patients to prevent delayed diagnosis and inappropriate treatments. In this review article, data have been collected by searching the available articles in the domestic and foreign journals using databases such as PubMed, PubMed Central, Medline, EBSCO, Google Scholar, and Embase with key words of Anosmia, Ageusia, Dysgeusia, Covid-19, and Coronavirus from 2019 to 2020. Among the relevant references, 38 authoritative articles were chosen. The data showed that it seems olfactory and taste function disorders are the obvious symptoms of Covid-19, which can occur independently or with other symptoms, but the pathogenesis is not well specified yet. Therefore, further studies are required to achieve a reliable result in this area.

摘要

冠状病毒疫情在全球引发了一场广泛的灾难。在研究中,有证据表明新冠病毒肺炎患者存在嗅觉和味觉功能障碍。这些症状可单独出现,也可能与干咳等其他症状相关。上述病症在患者中的发病机制及其临床特征尚不清楚。患者嗅觉功能障碍的发生率在29.64%至75.23%之间,味觉功能障碍的发生率在20.46%至68.95%之间。因此,包括耳鼻喉科专家和牙医在内的临床医生应关注这些患者的嗅觉丧失和味觉丧失症状,以防止诊断延误和治疗不当。在这篇综述文章中,通过使用PubMed、PubMed Central、Medline、EBSCO、谷歌学术和Embase等数据库,以嗅觉丧失、味觉丧失、味觉障碍、新冠病毒肺炎和冠状病毒为关键词,搜索国内外期刊上的现有文章来收集数据。在相关参考文献中,选取了38篇权威文章。数据表明,嗅觉和味觉功能障碍似乎是新冠病毒肺炎的明显症状,可单独出现或与其他症状同时出现,但其发病机制尚未明确。因此,需要进一步研究以在该领域取得可靠结果。

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