Mudra Rakshasa-Loots Arish, Laughton Barbara
Edinburgh Neuroscience, School of Biomedical Sciences, College of Medicine and Veterinary Medicine, The University of Edinburgh, Edinburgh, United Kingdom.
Department of Paediatrics and Child Health, Family Centre for Research With Ubuntu (FAMCRU), Stellenbosch University, Cape Town, South Africa.
Front Psychiatry. 2022 Feb 28;13:840912. doi: 10.3389/fpsyt.2022.840912. eCollection 2022.
Depression is a debilitating illness, and stigma associated with it often prevents people from seeking support. Easy-to-administer and culturally-specific diagnostic tools can allow for early screening for depression in primary care clinics, especially in resource-limited settings. In this pilot study, we will produce the first open-access isiXhosa-language version of the nine-item Patient Health Questionnaire (PHQ-9), a well-validated measure of depression incidence and severity, using a transcultural translation framework. We will validate this isiXhosa PHQ-9 in a small sample of adolescents living with HIV in Cape Town, South Africa who speak isiXhosa at home. Participants have previously completed the ASEBA Youth Self Report (YSR) form, and responses from the YSR will be used as a gold standard to validate the isiXhosa PHQ-9. If validated through this Registered Report, this isiXhosa PHQ-9 may be an invaluable culturally-specific tool for clinicians serving Xhosa people in identifying clinical or sub-clinical depression.
抑郁症是一种使人衰弱的疾病，与之相关的污名往往阻碍人们寻求帮助。易于使用且针对特定文化的诊断工具能够在基层医疗诊所实现对抑郁症的早期筛查，尤其是在资源有限的环境中。在这项试点研究中，我们将使用跨文化翻译框架，制作首个开放获取的科萨语版九项患者健康问卷（PHQ-9），这是一种经过充分验证的抑郁症发病率和严重程度测量工具。我们将在南非开普敦一小部分在家说科萨语的感染艾滋病毒青少年样本中验证这份科萨语PHQ-9。参与者此前已完成儿童行为评估系统青少年自评（YSR）表格，YSR的回答将作为验证科萨语PHQ-9的金标准。如果通过这份注册报告得到验证，这份科萨语PHQ-9对于为科萨人服务的临床医生识别临床或亚临床抑郁症而言，可能是一种非常宝贵的针对特定文化的工具。
