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德国纯种马繁育场中对苯并咪唑耐药的小型圆线虫的流行情况与防控

Prevalence and control of benzimidazole-resistant small strongyles on German thoroughbred studs.

作者信息

Bauer C, Merkt J C, Janke-Grimm G, Bürger H J

出版信息

Vet Parasitol. 1986 Aug;21(3):189-203. doi: 10.1016/0304-4017(86)90065-8.

Abstract

The prevalence of benzimidazole-resistant small strongyles was determined in a survey, conducted on 14 thoroughbred studs, which compared the faecal egg counts of groups of horses before and after treatment with the recommended doses of cambendazole (20 mg kg-1 b.w.) or febantel (6 mg kg-1 b.w.). Benzimidazole-resistant cyathostomes were found on all farms examined. Pyrantel pamoate (19 mg kg-1 b.w.), oxibendazole (10 mg kg-1 b.w.) and ivermectin (0.2 mg kg-1 b.w.) reduced the strongyle egg counts on these studs by 97-100% at 2 weeks post-treatment. However, 6 weeks after dosing the reduction of the strongyle egg output had decreased to an average of 67.8% (8.7-97.1%) with pyrantel pamoate and 51.2% (0-95.8%) with oxibendazole, whereas ivermectin still suppressed the egg counts by 98.2% (95-100%).

摘要

在一项对14个纯种马繁育场进行的调查中,测定了对苯并咪唑耐药的小型圆线虫的流行情况,该调查比较了用推荐剂量的坎苯达唑(20毫克/千克体重)或非班太尔(6毫克/千克体重)治疗前后马群的粪便虫卵计数。在所有检查的农场中均发现了对苯并咪唑耐药的杯冠属线虫。在治疗后2周,噻嘧啶(19毫克/千克体重)、奥苯达唑(10毫克/千克体重)和伊维菌素(0.2毫克/千克体重)使这些繁育场的圆线虫虫卵计数减少了97%-100%。然而,给药6周后,噻嘧啶使圆线虫虫卵排出量的减少平均降至67.8%(8.7%-97.1%),奥苯达唑为51.2%(0%-95.8%),而伊维菌素仍使虫卵计数抑制了98.2%(95%-100%)。

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