Bauer C, Merkt J C, Janke-Grimm G, Bürger H J
Vet Parasitol. 1986 Aug;21(3):189-203. doi: 10.1016/0304-4017(86)90065-8.
The prevalence of benzimidazole-resistant small strongyles was determined in a survey, conducted on 14 thoroughbred studs, which compared the faecal egg counts of groups of horses before and after treatment with the recommended doses of cambendazole (20 mg kg-1 b.w.) or febantel (6 mg kg-1 b.w.). Benzimidazole-resistant cyathostomes were found on all farms examined. Pyrantel pamoate (19 mg kg-1 b.w.), oxibendazole (10 mg kg-1 b.w.) and ivermectin (0.2 mg kg-1 b.w.) reduced the strongyle egg counts on these studs by 97-100% at 2 weeks post-treatment. However, 6 weeks after dosing the reduction of the strongyle egg output had decreased to an average of 67.8% (8.7-97.1%) with pyrantel pamoate and 51.2% (0-95.8%) with oxibendazole, whereas ivermectin still suppressed the egg counts by 98.2% (95-100%).
在一项对14个纯种马繁育场进行的调查中，测定了对苯并咪唑耐药的小型圆线虫的流行情况，该调查比较了用推荐剂量的坎苯达唑（20毫克/千克体重）或非班太尔（6毫克/千克体重）治疗前后马群的粪便虫卵计数。在所有检查的农场中均发现了对苯并咪唑耐药的杯冠属线虫。在治疗后2周，噻嘧啶（19毫克/千克体重）、奥苯达唑（10毫克/千克体重）和伊维菌素（0.2毫克/千克体重）使这些繁育场的圆线虫虫卵计数减少了97%-100%。然而，给药6周后，噻嘧啶使圆线虫虫卵排出量的减少平均降至67.8%（8.7%-97.1%），奥苯达唑为51.2%（0%-95.8%），而伊维菌素仍使虫卵计数抑制了98.2%（95%-100%）。
