Kulkarni Chidanand
Department of Ophthalmology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Taiwan J Ophthalmol. 2019 Sep 12;10(2):121-126. doi: 10.4103/tjo.tjo_19_19. eCollection 2020 Apr-Jun.
Although relation between Lens Opacities Classification System III (LOCS III) and nuclear density is established, no data are available about nuclear size at different LOCS III grades.
The aim of this study is to evaluate the relation between LOCS III grading of nuclear opacity obtained preoperatively and the size of the nucleus obtained during cataract surgery.
This was a prospective observational study carried out in a hospital attached to medical college.
Patients who underwent manual small-incision cataract surgery or extra-large temporal tunnel cataract extraction and gave consent were included in this study. Institutional Ethics Committee clearance was taken for the study. Preoperative LOCS III grading was obtained at slit-lamp biomicroscope. Ocular dimensions were obtained by preoperative immersion biometry. The thickness and diameter of the nucleus obtained by extraction were measured up to 10 μ accuracy. Data were analyzed for the change in nuclear thickness, nuclear diameter, age, lens thickness, and anterior chamber depth in relation to the LOCS III grade of the nucleus.
Statistical analysis used in this study was one-way ANOVA, mean, and range.
There was a significant increase ( < 0.05) in nuclear thickness, nuclear diameter, and age with increasing LOCS III grade of the nucleus. The change in nuclear size was linear between Grades 1 and 4. The nuclear size did not increase between Grades 4 and 5. It increased steeply from Grade 5 to Grade 6.9.
LOCS III grading of the nucleus can be utilized for determining the nuclear thickness and diameter preoperatively. These data can be helpful in adjusting machine parameters during phacoemulsification.
虽然晶状体混浊分类系统III（LOCS III）与核密度之间的关系已得到确立，但关于不同LOCS III分级下的核大小尚无数据。
本研究的目的是评估术前获得的核混浊的LOCS III分级与白内障手术中获得的核大小之间的关系。
这是一项在医学院附属医院进行的前瞻性观察性研究。
本研究纳入了接受手动小切口白内障手术或超大颞侧隧道白内障摘除术并签署知情同意书的患者。本研究已获得机构伦理委员会批准。术前在裂隙灯生物显微镜下进行LOCS III分级。术前通过浸没式生物测量法获得眼部尺寸。通过摘除获得的核的厚度和直径测量精度可达10微米。分析了核厚度、核直径、年龄、晶状体厚度和前房深度相对于核的LOCS III分级的变化情况。
本研究采用的统计分析方法为单因素方差分析、均值和范围。
随着核的LOCS III分级增加，核厚度、核直径和年龄均有显著增加（<0.05）。核大小在1级至4级之间呈线性变化。4级至5级之间核大小没有增加。从5级到6.9级急剧增加。
核的LOCS III分级可用于术前确定核厚度和直径。这些数据有助于在超声乳化手术过程中调整机器参数。
