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自主神经老化 - 用于量化健康老化过程中心血管自主功能变化的数据集。

Autonomic aging - A dataset to quantify changes of cardiovascular autonomic function during healthy aging.

机构信息

Lab for Autonomic Neuroscience, Imaging and Cognition (LANIC), Department of Psychosomatic Medicine and Psychotherapy, Jena University Hospital, Jena, Germany.

出版信息

Sci Data. 2022 Mar 23;9(1):95. doi: 10.1038/s41597-022-01202-y.

Abstract

Autonomic regulation of blood pressure and cardiac rhythm progressively declines with increasing age. Impaired cardiovascular control promotes a variety of age-related cardio-vascular conditions. This study aims to provide a database of high-resolution biological signals to describe the effect of healthy aging on cardiovascular regulation. Electrocardiogram and continuous non-invasive blood pressure signals were recorded simultaneously at rest in 1,121 healthy volunteers. With this database, we provide raw signals as well as basic demographic information such as gender and body mass index. To demonstrate validity of the acquired data, we present the well-known decline of heart rate variability with increasing age in this database.

摘要

血压和心率的自主调节随着年龄的增长而逐渐下降。心血管控制受损会促进多种与年龄相关的心血管疾病。本研究旨在提供一个高分辨率生物信号数据库,以描述健康衰老对心血管调节的影响。在 1121 名健康志愿者的休息状态下,同时记录心电图和连续无创血压信号。有了这个数据库,我们提供了原始信号以及基本的人口统计信息,如性别和体重指数。为了证明所获得数据的有效性,我们在此数据库中展示了众所周知的心率变异性随年龄增长而下降的趋势。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ded6/8943176/e368b8c552c8/41597_2022_1202_Fig1_HTML.jpg

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