Ahmad Zubair, Salman Saad, Khan Shahid Ali, Amin Abdul, Rahman Zia Ur, Al-Ghamdi Youssef O, Akhtar Kalsoom, Bakhsh Esraa M, Khan Sher Bahadar
Department of Chemistry, University of Swabi, Swabi 23561, Pakistan.
Faculty of Pharmacy, Capital University of Science and Technology, Islamabad 44000, Pakistan.
Gels. 2022 Mar 7;8(3):167. doi: 10.3390/gels8030167.
Hydrogels are three-dimensional, cross-linked, and supramolecular networks that can absorb significant volumes of water. Hydrogels are one of the most promising biomaterials in the biological and biomedical fields, thanks to their hydrophilic properties, biocompatibility, and wide therapeutic potential. Owing to their nontoxic nature and safe use, they are widely accepted for various biomedical applications such as wound dressing, controlled drug delivery, bone regeneration, tissue engineering, biosensors, and artificial contact lenses. Herein, this review comprises different synthetic strategies for hydrogels and their chemical/physical characteristics, and various analytical, optical, and spectroscopic tools for their characterization are discussed. A range of synthetic approaches is also covered for the synthesis and design of hydrogels. It will also cover biomedical applications such as bone regeneration, tissue engineering, and drug delivery. This review addressed the fundamental, general, and applied features of hydrogels in order to facilitate undergraduates, graduates, biomedical students, and researchers in a variety of domains.
水凝胶是三维、交联的超分子网络，能够吸收大量水分。由于其亲水性、生物相容性和广泛的治疗潜力，水凝胶是生物和生物医学领域最有前途的生物材料之一。由于其无毒性质和安全使用，它们被广泛应用于各种生物医学领域，如伤口敷料、控释药物、骨再生、组织工程、生物传感器和人工隐形眼镜。本文综述了水凝胶的不同合成策略及其化学/物理特性，并讨论了用于其表征的各种分析、光学和光谱工具。还涵盖了一系列用于水凝胶合成和设计的合成方法。它还将涵盖生物医学应用，如骨再生、组织工程和药物递送。这篇综述阐述了水凝胶的基本、一般和应用特性，以便为不同领域的本科生、研究生、生物医学专业学生和研究人员提供便利。
