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海洋生物抗氧化活性物质的研究进展

Recent Progress in Antioxidant Active Substances from Marine Biota.

作者信息

Vladkova Todorka, Georgieva Nelly, Staneva Anna, Gospodinova Dilyana

机构信息

Laboratory for Advanced Materials Research, University of Chemical Technology and Metallurgy (UCTM), 8 "St. Kl. Ohridski" Blvd, 1756 Sofia, Bulgaria.

Department of Biotechnology, University of Chemical Technology and Metallurgy (UCTM), 1756 Sofia, Bulgaria.

出版信息

Antioxidants (Basel). 2022 Feb 22;11(3):439. doi: 10.3390/antiox11030439.

Abstract

BACKGROUND

The well-recognized but not fully explored antioxidant activity of marine-biota-derived, biologically active substances has led to interest in their study as substitutes of antibiotics, antiaging agents, anticancer and antiviral drugs, and others. The aim of this review is to present the current state of the art of marine-biota-derived antioxidants to give some ideas for potential industrial applications.

METHODS

This review is an update for the last 5 years on the marine sources of natural antioxidants, different classes antioxidant compounds, and current derivation biotechnologies.

RESULTS

New marine sources of antioxidants, including byproducts and wastes, are presented, along with new antioxidant substances and derivation approaches.

CONCLUSIONS

The interest in high-value antioxidants from marine biota continues. Natural substances combining antioxidant and antimicrobial action are of particular interest because of the increasing microbial resistance to antibiotic treatments. New antioxidant substances are discovered, along with those extracted from marine biota collected in other locations. Byproducts and wastes provide a valuable source of antioxidant substances. The application of optimized non-conventional derivation approaches is expected to allow the intensification of the production and improvement in the quality of the derived substances. The ability to obtain safe, high-value products is of key importance for potential industrialization.

摘要

背景

海洋生物来源的生物活性物质具有公认但尚未充分探索的抗氧化活性,这引发了人们对其作为抗生素、抗衰老剂、抗癌和抗病毒药物等替代品进行研究的兴趣。本综述的目的是介绍海洋生物来源抗氧化剂的当前研究现状,为潜在的工业应用提供一些思路。

方法

本综述是对过去5年天然抗氧化剂的海洋来源、不同种类的抗氧化化合物以及当前提取生物技术的更新。

结果

介绍了新的海洋抗氧化剂来源,包括副产品和废弃物,以及新的抗氧化物质和提取方法。

结论

对来自海洋生物群的高价值抗氧化剂的兴趣持续存在。由于微生物对抗生素治疗的耐药性不断增加,兼具抗氧化和抗菌作用的天然物质尤其受到关注。新的抗氧化物质不断被发现,包括从其他地区采集的海洋生物中提取的物质。副产品和废弃物是抗氧化物质的宝贵来源。优化的非传统提取方法的应用有望提高产量并改善提取物的质量。获得安全、高价值产品的能力对于潜在的工业化至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/25d0/8944465/4fdccebcb867/antioxidants-11-00439-g001.jpg

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