Department of Dermatology, The Second Affiliated Hospital of Soochow University, Suzhou 215000, China.
Department of Dermatology and Venereology, Suzhou Medical College of Soochow University, Suzhou 215000, China.
Biomolecules. 2022 Mar 15;12(3):454. doi: 10.3390/biom12030454.
Histamine intolerance (HIT) is a common disorder associated with impaired histamine metabolism. Notwithstanding, it is often misdiagnosed as other diseases because of its lack of specific clinical manifestations. HIT did not gain traction until the early 21st century. In this review, we will focus on the latest research and elaborate on the clinical manifestations of HIT, including its manifestations in special populations such as atopic dermatitis (AD) and chronic urticaria (CU), as well as the latest understanding of its etiology and pathogenesis. In addition, we will explore the latest treatment strategies for HIT and the treatment of specific cases.
组胺不耐受（HIT）是一种常见的疾病，与组胺代谢受损有关。然而，由于其缺乏特异性的临床表现，常被误诊为其他疾病。HIT 直到 21 世纪初才引起关注。在这篇综述中，我们将重点介绍 HIT 的最新研究进展，并详细阐述其临床表现，包括其在特应性皮炎（AD）和慢性荨麻疹（CU）等特殊人群中的表现，以及对其病因和发病机制的最新认识。此外，我们还将探讨 HIT 的最新治疗策略和具体病例的治疗方法。
