Department of Statistical Science, Baylor University, Waco, TX 76798-7140, USA.
Int J Environ Res Public Health. 2022 Mar 11;19(6):3327. doi: 10.3390/ijerph19063327.
The COVID-19 pandemic that began at the end of 2019 has caused hundreds of millions of infections and millions of deaths worldwide. COVID-19 posed a threat to human health and profoundly impacted the global economy and people's lifestyles. The United States is one of the countries severely affected by the disease. Evidence shows that the spread of COVID-19 was significantly underestimated in the early stages, which prevented governments from adopting effective interventions promptly to curb the spread of the disease. This paper adopts a Bayesian hierarchical model to study the under-reporting of COVID-19 at the state level in the United States as of the end of April 2020. The model examines the effects of different covariates on the under-reporting and accurate incidence rates and considers spatial dependency. In addition to under-reporting (false negatives), we also explore the impact of over-reporting (false positives). Adjusting for misclassification requires adding additional parameters that are not directly identified by the observed data. Informative priors are required. We discuss prior elicitation and include R functions that convert expert information into the appropriate prior distribution.
自 2019 年末开始的 COVID-19 大流行已在全球范围内导致数亿人感染和数百万人死亡。COVID-19 对人类健康构成威胁,并深刻影响了全球经济和人们的生活方式。美国是受该疾病严重影响的国家之一。有证据表明,在疾病早期,COVID-19 的传播被严重低估,这使得各国政府无法及时采取有效干预措施来遏制疾病的传播。本文采用贝叶斯层次模型研究截至 2020 年 4 月底美国各州 COVID-19 的漏报情况。该模型检验了不同协变量对漏报和准确发病率的影响,并考虑了空间相关性。除了漏报(假阴性),我们还探讨了过度报告(假阳性)的影响。调整误分类需要添加无法直接由观察数据确定的附加参数。需要信息先验。我们讨论了先验的引出,并包含了将专家信息转换为适当先验分布的 R 函数。