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羟羧氧酰胺菌素治疗伤寒热

Moxalactam in the treatment of typhoid fever.

作者信息

Uwaydah M, Vartivarian S, Shatila S, Raad I, Harakeh H, Nassar N T

出版信息

Antimicrob Agents Chemother. 1986 Aug;30(2):338-9. doi: 10.1128/AAC.30.2.338.

DOI:10.1128/AAC.30.2.338
PMID:3532946
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC180549/
Abstract

Moxalactam therapy was evaluated in 25 patients with typhoid fever. A satisfactory initial response was observed in all cases. Treatment for 3 days resulted in a much higher relapse rate (three of five patients) than did treatment for 5 days (one of nine patients). None of the 11 patients treated for 10 to 11 days relapsed. Moxalactam is effective in typhoid fever, but its use is better restricted to special indications.

摘要

对25例伤寒患者进行了羟羧氧酰胺菌素治疗评估。所有病例均观察到令人满意的初始反应。治疗3天的复发率（5例中有3例）远高于治疗5天的复发率（9例中有1例）。接受10至11天治疗的11例患者均未复发。羟羧氧酰胺菌素对伤寒有效，但最好仅限于特殊适应症使用。

相似文献

1
Moxalactam in the treatment of typhoid fever.羟羧氧酰胺菌素治疗伤寒热
Antimicrob Agents Chemother. 1986 Aug;30(2):338-9. doi: 10.1128/AAC.30.2.338.
2
Comparative clinical trial of amoxycillin and chloramphenicol in the treatment of typhoid in adults.阿莫西林与氯霉素治疗成人伤寒的比较临床试验。
J Int Med Res. 1979;7(3):247-52. doi: 10.1177/030006057900700314.
3
Comparative efficacies of aztreonam and chloramphenicol in children with typhoid fever.
Pediatr Infect Dis J. 1990 Jan;9(1):44-8. doi: 10.1097/00006454-199001000-00010.
4
Moxalactam versus clindamycin plus tobramycin in the treatment of obstetric and gynecologic infections.羟羧氧酰胺菌素与克林霉素加妥布霉素治疗妇产科感染的比较
Am J Obstet Gynecol. 1985 Aug 1;152(7 Pt 1):808-17. doi: 10.1016/s0002-9378(85)80068-5.
5
Clinical experience with pefloxacin in the therapy of typhoid fever.
Infection. 1989 Mar-Apr;17(2):86-7. doi: 10.1007/BF01646882.
6
Mecillinam in enteric fever.美西林治疗伤寒。
Br Med J. 1979 Mar 3;1(6163):586-7. doi: 10.1136/bmj.1.6163.586.
7
Open study on efficacy and safety of levofloxacin in treatment of uncomplicated typhoid fever.
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8
Multicenter clinical trials comparing cefotetan with moxalactam or cefoxitin as therapy for obstetric and gynecologic infections.
Am J Surg. 1988 May 31;155(5A):56-60. doi: 10.1016/s0002-9610(88)80214-9.
9
Ceftazidime in treatment of urinary tract infection in patients with spinal cord injury: comparison with moxalactam.头孢他啶治疗脊髓损伤患者尿路感染：与拉氧头孢比较
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Clinical trial of cefotaxime in patients with typhoid fever.头孢噻肟治疗伤寒患者的临床试验。
Clin Ther. 1985;7(4):448-51.

本文引用的文献

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Treatment of typhoid fever with cefamandole.用头孢孟多治疗伤寒热。
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Salmonella typhi in vivo acquires resistance to both chloramphenicol and co-trimoxazole.伤寒沙门氏菌在体内对氯霉素和复方新诺明均产生耐药性。
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7
The antibiotic treatment of typhoid fever.伤寒热的抗生素治疗。
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8
Cefazolin in the treatment of acute enteric fever.头孢唑林治疗急性肠热症。
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