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羟羧氧酰胺菌素治疗伤寒热

Moxalactam in the treatment of typhoid fever.

作者信息

Uwaydah M, Vartivarian S, Shatila S, Raad I, Harakeh H, Nassar N T

出版信息

Antimicrob Agents Chemother. 1986 Aug;30(2):338-9. doi: 10.1128/AAC.30.2.338.

Abstract

Moxalactam therapy was evaluated in 25 patients with typhoid fever. A satisfactory initial response was observed in all cases. Treatment for 3 days resulted in a much higher relapse rate (three of five patients) than did treatment for 5 days (one of nine patients). None of the 11 patients treated for 10 to 11 days relapsed. Moxalactam is effective in typhoid fever, but its use is better restricted to special indications.

摘要

对25例伤寒患者进行了羟羧氧酰胺菌素治疗评估。所有病例均观察到令人满意的初始反应。治疗3天的复发率(5例中有3例)远高于治疗5天的复发率(9例中有1例)。接受10至11天治疗的11例患者均未复发。羟羧氧酰胺菌素对伤寒有效,但最好仅限于特殊适应症使用。

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本文引用的文献

1
Treatment of typhoid fever with cefamandole.用头孢孟多治疗伤寒热。
Antimicrob Agents Chemother. 1984 Sep;26(3):426-7. doi: 10.1128/AAC.26.3.426.
2
Moxalactam--absorption, excretion, distribution, and metabolism.
Rev Infect Dis. 1982 Nov-Dec;4 Suppl:S569-80. doi: 10.1093/clinids/4.supplement_3.s569.
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In vitro and in vivo antibacterial activity of moxalactam, an oxa-beta-lactam antibiotic.
Rev Infect Dis. 1982 Nov-Dec;4 Suppl:S501-10. doi: 10.1093/clinids/4.supplement_3.s501.
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Acta Trop. 1980 Sep;37(3):275-80.
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Choice of antimicrobial agents in enteric fever.伤寒中抗菌药物的选择
J Antimicrob Chemother. 1975 Jun;1(2):135-7. doi: 10.1093/jac/1.2.135.
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The antibiotic treatment of typhoid fever.伤寒热的抗生素治疗。
J Antimicrob Chemother. 1977 Sep;3(5):382-3. doi: 10.1093/jac/3.5.382.
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Cefazolin in the treatment of acute enteric fever.头孢唑林治疗急性肠热症。
Antimicrob Agents Chemother. 1976 Jul;10(1):52-6. doi: 10.1128/AAC.10.1.52.

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