Uwaydah M, Nassar N T, Harakeh H, Vartivarian S, Talhouk A, Kantarjian H
Antimicrob Agents Chemother. 1984 Sep;26(3):426-7. doi: 10.1128/AAC.26.3.426.
Cefamandole therapy was evaluated in nine patients with typhoid fever. Six patients, including all five who received the antibiotic by continuous intravenous drip (8.0 g daily), were cured. Dosage schedules resulting in maintenance of antibiotic concentrations in serum high above the MIC seemed to correlate well with treatment success.
对9例伤寒热患者进行了头孢孟多治疗评估。6例患者治愈,包括所有5例通过持续静脉滴注(每日8.0克)接受抗生素治疗的患者。使血清中抗生素浓度维持在远高于最低抑菌浓度水平的给药方案似乎与治疗成功密切相关。