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酿酒酵母中的隐性无义抑制基因:作用光谱、互补群及图谱位置。

Recessive nonsense suppressors in Saccharomyces cerevisiae: action spectra, complementation groups and map positions.

作者信息

Ono B, Ishino-Arao Y, Tanaka M, Awano I, Shinoda S

出版信息

Genetics. 1986 Oct;114(2):363-74. doi: 10.1093/genetics/114.2.363.

Abstract

Three genes SUP111, SUP112 and SUP113 of Saccharomyces cerevisiae have been identified that can mutate to give recessive omnipotent nonsense suppressors. Alleles of these loci can also act as allosuppressors; that is, different phenotypes, due apparently to different efficiencies of suppression, can result from different alleles at a given locus. The SUP111, SUP112 and SUP113 loci map to the right arms of chromosomes VIII, VII and XIII, respectively.

摘要

已鉴定出酿酒酵母的三个基因SUP111、SUP112和SUP113,它们发生突变后可产生隐性全能无义抑制子。这些位点的等位基因也可作为别位抑制子;也就是说,由于抑制效率明显不同,给定位点的不同等位基因可导致不同的表型。SUP111、SUP112和SUP113位点分别定位于第八条、第七条和第十三条染色体的右臂上。

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