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合生素对肉鸡生长性能、消化性能、免疫和抗氧化性能的影响。

Effects of synbiotic on growth, digestibility, immune and antioxidant performance in broilers.

机构信息

Academy of National Food and Strategic Reserves Administration, Beijing, PR China; College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, PR China.

Academy of National Food and Strategic Reserves Administration, Beijing, PR China.

出版信息

Animal. 2022 Apr;16(4):100497. doi: 10.1016/j.animal.2022.100497. Epub 2022 Mar 23.

DOI:10.1016/j.animal.2022.100497
PMID:35338905
Abstract

The overuse of in-feed antibiotics has been associated with serious issues, including the developing of antibiotic-resistant pathogens and causing drug residues in poultry products. To date, many countries have restricted the use of growth-promoting antibiotics in food animals, resulting in the increased need for effective alternatives to in-feed antibiotic. Synbiotics, which are composed of probiotics and prebiotics, have been shown to act synergistically when applied simultaneously. Thus, this study investigated the effects of a synbiotic, composed of microencapsulated Lactobacillus plantarum (MLP) and fructooligosaccharide (FOS), on growth, immune and antioxidant parameters, and digestibility of calcium and phosphorus in broilers. A total of 168 newly hatched male broilers were randomly allotted to three dietary groups (n = 7): (1) a corn-soybean meal basal diet (CON); (2) basal diet + synbiotic (SYN); and (3) basal diet + aureomycin (ANT). Compared with the CON, chickens had greater average daily gain and digestibility of calcium and phosphorus in the SYN group (P < 0.05). In the SYN and ANT group, serum IgA, IgG, and IL-10 levels were higher, while the serum TNF-α, IL-2, and IL-6 levels were reduced (P < 0.05) compared to CON. Compared with CON, the level of serum malondialdehyde was lower (P < 0.05) and SOD level was higher (P < 0.05) in either SYN or ANT group. No significant differences in populations of Escherichia coli were seen in chickens among the three groups, whereas, the populations of Lactobacillus were higher (P < 0.05) in chickens in the SYN group compared with those in CON and ANT groups. Taken together, the addition of SYN, consisting of MLP and FOS, had benefits on growth, immune and antioxidant parameters, and digestibility of calcium and phosphorus, indicating its potential to serve as a substitute for antibiotics in broiler feeding.

摘要

饲用抗生素的过度使用与许多严重问题相关,包括抗生素耐药病原体的出现以及禽产品中的药物残留。迄今为止,许多国家已经限制了在食用动物中使用促生长抗生素,这导致对饲用抗生素替代品的需求增加。益生菌和益生元组成的合生元在同时使用时表现出协同作用。因此,本研究调查了由微囊包被的植物乳杆菌(MLP)和低聚果糖(FOS)组成的合生元对肉鸡生长、免疫和抗氧化参数以及钙和磷消化率的影响。总共 168 只刚孵化的雄性肉鸡被随机分配到三个日粮组(n=7):(1)玉米-豆粕基础日粮(CON);(2)基础日粮+合生元(SYN);和(3)基础日粮+金霉素(ANT)。与 CON 相比,SYN 组肉鸡的平均日增重和钙磷消化率更高(P<0.05)。在 SYN 和 ANT 组中,血清 IgA、IgG 和 IL-10 水平升高,而血清 TNF-α、IL-2 和 IL-6 水平降低(P<0.05)。与 CON 相比,SYN 或 ANT 组血清丙二醛水平降低(P<0.05),SOD 水平升高(P<0.05)。三组肉鸡血清大肠杆菌数量无显著差异,而 SYN 组肉鸡乳酸菌数量高于 CON 和 ANT 组(P<0.05)。综上所述,添加由 MLP 和 FOS 组成的 SYN 对生长、免疫和抗氧化参数以及钙磷消化率有益,表明其有潜力替代肉鸡饲养中的抗生素。

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