衰老、最大摄氧量、熵和 COVID-19。

Aging, VO max, entropy, and COVID-19.

机构信息

Spedding Research Solutions SAS, 6 Rue Ampère, 78110 Le Vésinet, France.

IRMES (Institut de Recherche bioMédicale et d'Épidémiologie du Sport), INSEP (Institut national du sport, de l'expertise et de la performance), 11, avenue du Tremblay, 75012 Paris, France.

出版信息

Indian J Pharmacol. 2022 Jan-Feb;54(1):58-62. doi: 10.4103/ijp.ijp_442_21.

DOI:10.4103/ijp.ijp_442_21

PMID:35343209

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9012415/

Abstract

The decline in human performance with age at 5000 m, an athletic event requiring high VO max, is remarkably precise, and unavoidable, and related to entropy, even at an individual level. Women and men show an identical age-related decline, up to ~100 years old. The precision of the decline shows the limitations for therapy of aging. Mortality incidence for COVID-19 shows a similar relationship. We propose that initial VO max has a critical role in COVID sensitivity because of the direct relationship of disease severity with oxygen use, and the parallel decline in aging.

摘要

在 5000 米这样一项需要高最大摄氧量的运动项目中，人类的表现能力会随年龄而下降，这种下降在个体水平上也是非常精确且不可避免的，与熵有关。女性和男性的衰老相关下降是一样的，最高可达 100 岁左右。下降的精确性表明了衰老治疗的局限性。COVID-19 的死亡率也表现出类似的关系。我们提出，初始最大摄氧量在 COVID 敏感性中起着关键作用，因为疾病严重程度与氧气利用以及衰老的平行下降直接相关。