Department of Biotechnology Engineering, NMAM Institute of Technology, Visvesvaraya Technological University, Nitte, India.
J Cosmet Dermatol. 2022 Oct;21(10):4999-5009. doi: 10.1111/jocd.14949. Epub 2022 Apr 11.
Studies show that the extensive use of chemical shampoos has a negative impact on health. Given the recent trends, the use of herbal shampoos is gaining importance. Cyclea peltata is a common plant in Kerala's coastal region that has traditionally been used to aid in wound healing, allergy relief, and hair and scalp improvement. Greenly produced silver nanoparticles made from plant sources have a wide range of medical applications.
The main objective is to optimize the base of the shampoo with better solid content by OFAT studies and characterize the silver nanoparticles synthesized using post optimized shampoo base.
Cyclea peltata leaves were fermented with Lactobacillus plantarum for the shampoo formulation, substituting the chemical basis gelatin with an herbal fermented foundation. Silver nanoparticles combined with an herbal formulation should be as safe as herbal shampoo while also being as effective as chemical shampoo. Variation of concentration of Cyclea peltata leaf powder, variation of sucrose concentration, variation of concentration of yeast extract, variation of L. plantarum inoculum, variation of temperature, variation of agitation speed, and variation of time were all studied using the OFAT (One Factor At a Time) method. Silver nanoparticles synthesized using post optimized shampoo bases were also characterized by particle size, zeta potential, and FTIR analysis in order to better understand their properties.
The results clearly indicated that all the six factors had a significant effect on the growth and production of EPS. The pH considered for the shampoo base is above 5 so as to maintain the acidic mantle of the scalp. Green synthesized silver nanoparticles from post optimized shampoo base were obtained within 17th hour of incubation, with single surface plasmon resonance at 420 nm. Nanoparticles showed a peak at -11.6 mv of zeta potential which means that the particles are less agglomerative and stable. Similar groups were seen in ftir spectrum of fermented silver nanoparticles and the plant extract which confirmed the capping of nanoparticles with plant phytochemicals.
The study successfully prepared and characterized green synthesized silver nanoparticles from post optimized shampoo base and also optimized the shampoo base based on the EPS production. Characterization of the silver nanoparticles found that the nanoparticles synthesized were stable, less agglomerative, and had several useful components present in it.
研究表明，广泛使用化学洗发水对健康有负面影响。鉴于最近的趋势，草药洗发水的使用越来越重要。Cyclea peltata 是喀拉拉邦沿海地区的一种常见植物，传统上用于帮助伤口愈合、缓解过敏和改善头发和头皮。从植物来源中绿色生产的银纳米粒子具有广泛的医疗应用。
主要目标是通过 OFAT 研究优化具有更好固含量的洗发水基础，并对使用优化后的洗发水基础合成的银纳米粒子进行表征。
用植物乳杆菌发酵 Cyclea peltata 叶来制备洗发水配方，用草药发酵基础代替化学基础明胶。银纳米粒子与草药配方结合，应该像草药洗发水一样安全，同时也像化学洗发水一样有效。使用 OFAT（一次一个因素）方法研究了 Cyclea peltata 叶粉浓度的变化、蔗糖浓度的变化、酵母提取物浓度的变化、L. plantarum 接种物的变化、温度的变化、搅拌速度的变化和时间的变化。还通过粒径、zeta 电位和 FTIR 分析对使用优化后的洗发水基础合成的银纳米粒子进行了表征，以便更好地了解其性质。
结果清楚地表明，所有六个因素对 EPS 的生长和生产都有显著影响。洗发水基础的 pH 值考虑在 5 以上，以保持头皮的酸性保护层。在 17 小时的孵育后，从优化后的洗发水基础中获得了绿色合成的银纳米粒子，在 420nm 处有单一的表面等离子体共振。纳米粒子的 zeta 电位显示出-11.6mV 的峰值，这意味着颗粒的聚集性和稳定性较差。在发酵银纳米粒子和植物提取物的 ftir 光谱中观察到相似的基团，这证实了纳米粒子被植物次生代谢物包裹。
该研究成功地从优化后的洗发水基础中制备和表征了绿色合成的银纳米粒子，并基于 EPS 生产对洗发水基础进行了优化。对银纳米粒子的表征发现，合成的纳米粒子稳定、聚集性低，并且含有几种有用的成分。
