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早餐消费频率与血脂异常有关:一项针对工作人群的回顾性队列研究。

Breakfast consumption frequency is associated with dyslipidemia: a retrospective cohort study of a working population.

机构信息

Big Data Center, Nanfang Hospital, Southern Medical University, 510515, Guangzhou, China.

Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, 510515, Guangzhou, China.

出版信息

Lipids Health Dis. 2022 Mar 27;21(1):33. doi: 10.1186/s12944-022-01641-x.

Abstract

BACKGROUND

Dyslipidemia is a significant contributor to cardiovascular and cerebrovascular diseases. Research on the relationship between breakfast consumption frequency and dyslipidemia in the working population is lacking. Therefore, we aimed to investigate this relationship based on a retrospective cohort study of a large working population in China.

METHODS

This retrospective cohort study used data from the physical examinations and questionnaire survey of working participants at Nanfang Hospital from January 20, 2015 to October 16, 2020. Univariate and multivariate analyses were conducted to explore the relationship between breakfast consumption frequency and dyslipidemia in this working population (n = 7644).

RESULTS

The prevalence of dyslipidemia among the participants was 26.4%. The univariate logistic regression test showed that the breakfast consumption frequency was inversely correlated with dyslipidemia. After adjusting for multiple factors, such as sex, age, body mass index, hypertension, hyperuricaemia, diabetes, smoking status, alcohol consumption, education level, marital status, long-term exposure to kitchen oil fumes, attending business dinners, and sleep time, it was found that breakfast consumption remained inversely associated with dyslipidaemia. The odds ratio for daily breakfast consumption was 0.466 (95% confidence interval 0.283-0.770, P = 0.003). After adjusting for confounding factors, we found that the higher the frequency of breakfast consumption, the lower the odds ratios for hypertriglyceridaemia.

CONCLUSIONS

This study demonstrated that breakfast consumption frequency was inversely correlated with dyslipidemia. The higher the frequency of breakfast, the lower the risk of hypertriglyceridaemia. This study provides a basis on which dietary suggestions for the working population and lifestyle guidance for patients with a clinical need to prevent dyslipidemia can be made.

摘要

背景

血脂异常是心血管和脑血管疾病的重要致病因素。关于早餐食用频率与工作人群血脂异常之间关系的研究较少。因此,我们旨在通过对中国一大工作人群的回顾性队列研究来探讨这种关系。

方法

本回顾性队列研究使用了 2015 年 1 月 20 日至 2020 年 10 月 16 日南方医院体检和问卷调查中工作参与者的数据。采用单因素和多因素分析方法探讨了该工作人群(n=7644)中早餐食用频率与血脂异常之间的关系。

结果

参与者的血脂异常患病率为 26.4%。单因素 logistic 回归检验显示,早餐食用频率与血脂异常呈负相关。在调整性别、年龄、体重指数、高血压、高尿酸血症、糖尿病、吸烟状态、饮酒、教育水平、婚姻状况、长期接触厨房油烟、参加商务晚宴和睡眠时间等多种因素后,发现早餐食用与血脂异常仍呈负相关。每天吃早餐的优势比为 0.466(95%置信区间 0.283-0.770,P=0.003)。在调整混杂因素后,我们发现早餐食用频率越高,患高甘油三酯血症的优势比越低。

结论

本研究表明,早餐食用频率与血脂异常呈负相关。早餐食用频率越高,患高甘油三酯血症的风险越低。本研究为针对工作人群的饮食建议和有临床需要预防血脂异常的患者的生活方式指导提供了依据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f715/8966363/3ada0b6d2df0/12944_2022_1641_Fig1_HTML.jpg

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