School of Nursing, Fujian University of Traditional Chinese Medicine, Fuzhou, China.
School of Medicine, Xiamen University, Xiamen, China.
BMJ Open. 2022 Mar 28;12(3):e058533. doi: 10.1136/bmjopen-2021-058533.
This study aims to systematically evaluate the effectiveness of nurse-led cares on cardiovascular risk factors among individuals with type 2 diabetes mellitus.
Systematic review and meta-analysis.
The electronic databases PubMed, EMBASE, CINAHL and Cochrane Library databases were searched for randomised controlled trials of nurse-led care for individuals with type 2 diabetes mellitus (T2DM) published in English from inception to 23 December 2021. Random effects models were used to calculate weighted mean differences (WMD) with 95%CI.
13 articles were included in the meta-analysis, with a total of3757 participants. Considering baseline measurements, pooled analysis showed that nurse-led care significantly decreased the glycosylated haemoglobin (HbA1c) (WMD=-0.68 mmol/L; 95% CI -0.85 to -0.52; p<0.001), body mass index (BMI) (WMD=-0.54 kg/m; 95% CI: -0.97 to -0.11; p=0.01) and systolic blood pressure (SBP) (WMD=-1.17 mmHg; 95% CI: -2.11 to -0.22; p=0.02) for patients with T2DM. But there was no difference in low-density lipoprotein cholesterol (LDL-c) (WMD=-2.50 mg/dL ; 95% CI: -5.07 to 0.08; p=0.06) between the nurse-led and control groups.
Nurse-led care is an effective and accessible intervention that could improve HbA1c, SBP, BMI levels among individuals with T2DM.
CRD42021248275.
本研究旨在系统评估护士主导的护理对 2 型糖尿病患者心血管危险因素的有效性。
系统评价和荟萃分析。
检索了 PubMed、EMBASE、CINAHL 和 Cochrane Library 数据库，以获取截至 2021 年 12 月 23 日发表的英文随机对照试验，研究对象为 2 型糖尿病患者的护士主导护理。使用随机效应模型计算加权均数差（WMD）及其 95%置信区间（CI）。
纳入 13 项荟萃分析，共计 3757 名参与者。考虑到基线测量值，汇总分析显示，护士主导的护理显著降低了糖化血红蛋白（HbA1c）（WMD=-0.68mmol/L；95%CI：-0.85 至 -0.52；p<0.001）、体重指数（BMI）（WMD=-0.54kg/m；95%CI：-0.97 至 -0.11；p=0.01）和收缩压（SBP）（WMD=-1.17mmHg；95%CI：-2.11 至 -0.22；p=0.02）。但护士主导组与对照组之间的低密度脂蛋白胆固醇（LDL-c）（WMD=-2.50mg/dL；95%CI：-5.07 至 0.08；p=0.06）差异无统计学意义。
护士主导的护理是一种有效且易于实施的干预措施，可改善 2 型糖尿病患者的 HbA1c、SBP 和 BMI 水平。
CRD42021248275。
