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Int J Food Microbiol. 2020 Mar 16;317:108479. doi: 10.1016/j.ijfoodmicro.2019.108479. Epub 2019 Dec 12.
3
Identification of Hepatitis E Virus in Bovine and Porcine Raw Livers.鉴定牛和猪生肝脏中的戊型肝炎病毒。
J Microbiol Biotechnol. 2019 Dec 28;29(12):2022-2025. doi: 10.4014/jmb.1910.10059.
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Hepatitis E virus (HEV)-The Future.戊型肝炎病毒(HEV)——未来展望。
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[Detection of HEV RNA amounts and genotypes in raw milks obtained from different animals].[不同动物来源生鲜乳中戊型肝炎病毒RNA含量及基因型的检测]
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Seroprevalence of hepatitis E in adults in Brazil: a systematic review and meta-analysis.巴西成年人戊型肝炎血清流行率:系统评价和荟萃分析。
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Evidence for an unknown agent antigenically related to the hepatitis E virus in dairy cows in the United States.在美国奶牛中发现一种与戊型肝炎病毒抗原相关的未知病原体。
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Evidence of increased Hepatitis E virus exposure in Lao villagers with contact to ruminants.老挝与反刍动物有接触的村民中戊型肝炎病毒暴露增加的证据。
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巴西南里奥格兰德州屠宰牛肝脏中的戊型肝炎病毒 3 基因型。

Hepatitis E virus genotype 3 in bovine livers slaughtered in the state of Rio Grande do Sul, Brazil.

机构信息

Laboratório de Microbiologia Molecular, Universidade Feevale, Rodovia ERS-239, Nº 2755, Prédio Vermelho, Piso 1, sala 103, Vila Nova, Novo Hamburgo, RS, CEP 93525-075, Brazil.

出版信息

Braz J Microbiol. 2022 Sep;53(3):1115-1120. doi: 10.1007/s42770-022-00741-1. Epub 2022 Mar 30.

DOI:10.1007/s42770-022-00741-1
PMID:35355235
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9433617/
Abstract

Foodborne viruses are becoming a global concern as they overwhelm the health system and have the potential to spread globally. Among them, some genotypes of hepatitis E virus (HEV), which is one of the main causes of acute hepatitis in humans, have a zoonotic potential and can be found in foods of animal origin. Infected farm animals are a possible source of the virus, either by direct contact with animal excreta or meat. In the present study, 240 bovine liver samples from slaughter carried out in Rio Grande do Sul (RS), Brazil, were analyzed and tested for the presence of HEV. After performing PCR, 5.4% of positive samples were observed. One of the samples could be identified by molecular phylogenetic analysis as belonging to genotype 3, for which pigs are natural reservoirs, but has not been reported in bovine meat and products so far.

摘要

食源性病原体日益受到全球关注,因为它们对卫生系统造成冲击,并可能在全球范围内传播。其中,一些基因型的戊型肝炎病毒(HEV)是人患急性肝炎的主要病因之一,具有动物源性病原体特性,可能存在于动物源性食品中。受感染的农场动物可能是病毒的潜在传染源,其传播途径可能是直接接触动物粪便或肉类。在本研究中,对巴西南里奥格兰德州(RS)屠宰的 240 份牛肝样本进行了分析并检测了 HEV 的存在情况。通过 PCR 检测,观察到 5.4%的阳性样本。通过分子系统进化分析,其中一个样本被鉴定为基因型 3,该基因型的天然宿主是猪,但目前尚未在牛肉和牛肉制品中报告过。