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冠状动脉血流缓慢:发病机制与临床意义

Slow Coronary Blood Flow: Pathogenesis and Clinical Implications.

作者信息

Aparicio Andrea, Cuevas Javier, Morís César, Martín María

机构信息

Area de Gestión Clínica del Corazón, Hospital Universitario Central de Asturias Oviedo, Asturias, Spain.

出版信息

Eur Cardiol. 2022 Mar 14;17:e08. doi: 10.15420/ecr.2021.46. eCollection 2022 Feb.

DOI:10.15420/ecr.2021.46
PMID:35356630
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8941644/
Abstract

Coronary slow flow (CSF) phenomenon, also known as cardiac syndrome Y, is defined as the delayed opacification of the coronary vasculature at the distal level. Different hypotheses and theories have been postulated about its substrate and mechanism, such as microvascular and endothelial dysfunction. Several studies have confirmed that CSF is a cause of ischaemia detected by non-invasive testing. Clinically, it can present as angina pectoris, acute coronary syndrome and sudden cardiac death. It has an incidence of 1-5% in patients undergoing coronary angiography and has been most frequently found in young men who are smokers with metabolic syndrome. There are no established treatments for CSF and further studies are still necessary.

摘要

冠状动脉慢血流(CSF)现象,也称为Y综合征,定义为冠状动脉远端血管造影剂延迟显影。关于其病理基础和机制有多种假说和理论,如微血管和内皮功能障碍。多项研究证实,CSF是无创检测发现的缺血原因。临床上,它可表现为心绞痛、急性冠状动脉综合征和心源性猝死。在接受冠状动脉造影的患者中,其发生率为1%至5%,最常见于患有代谢综合征的吸烟年轻男性。目前尚无针对CSF的确切治疗方法,仍需进一步研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04f0/8941644/8d004da47b6e/ecr-17-e08-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04f0/8941644/d8bb49698933/ecr-17-e08-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04f0/8941644/8d004da47b6e/ecr-17-e08-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04f0/8941644/d8bb49698933/ecr-17-e08-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04f0/8941644/8d004da47b6e/ecr-17-e08-g002.jpg

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