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降低内镜垂体手术外科工作流程识别中的预测波动。

Reducing prediction volatility in the surgical workflow recognition of endoscopic pituitary surgery.

机构信息

Wellcome/EPSRC Centre for Interventional and Surgical Sciences, University College London, London, United Kingdom.

Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, London, United Kingdom.

出版信息

Int J Comput Assist Radiol Surg. 2022 Aug;17(8):1445-1452. doi: 10.1007/s11548-022-02599-y. Epub 2022 Apr 1.

Abstract

PURPOSE

Workflow recognition can aid surgeons before an operation when used as a training tool, during an operation by increasing operating room efficiency, and after an operation in the completion of operation notes. Although several methods have been applied to this task, they have been tested on few surgical datasets. Therefore, their generalisability is not well tested, particularly for surgical approaches utilising smaller working spaces which are susceptible to occlusion and necessitate frequent withdrawal of the endoscope. This leads to rapidly changing predictions, which reduces the clinical confidence of the methods, and hence limits their suitability for clinical translation.

METHODS

Firstly, the optimal neural network is found using established methods, using endoscopic pituitary surgery as an exemplar. Then, prediction volatility is formally defined as a new evaluation metric as a proxy for uncertainty, and two temporal smoothing functions are created. The first (modal, [Formula: see text]) mode-averages over the previous n predictions, and the second (threshold, [Formula: see text]) ensures a class is only changed after being continuously predicted for n predictions. Both functions are independently applied to the predictions of the optimal network.

RESULTS

The methods are evaluated on a 50-video dataset using fivefold cross-validation, and the optimised evaluation metric is weighted-[Formula: see text] score. The optimal model is ResNet-50+LSTM achieving 0.84 in 3-phase classification and 0.74 in 7-step classification. Applying threshold smoothing further improves these results, achieving 0.86 in 3-phase classification, and 0.75 in 7-step classification, while also drastically reducing the prediction volatility.

CONCLUSION

The results confirm the established methods generalise to endoscopic pituitary surgery, and show simple temporal smoothing not only reduces prediction volatility, but actively improves performance.

摘要

目的

工作流程识别可作为一种培训工具,在手术前帮助外科医生,在手术中提高手术室效率,在手术后完成手术记录。尽管已经应用了几种方法,但它们仅在少数几个手术数据集上进行了测试。因此,它们的泛化能力尚未得到充分验证,特别是对于使用较小工作空间的手术方法,这些方法容易发生遮挡,需要频繁撤回内窥镜。这导致预测迅速变化,降低了方法的临床可信度,因此限制了它们在临床转化中的适用性。

方法

首先,使用既定方法找到最佳神经网络,以内镜垂体手术为例。然后,正式将预测波动性定义为新的评估指标,以表示不确定性,并创建两个时间平滑函数。第一个(模态,[公式:见文本])对前 n 个预测进行平均,第二个(阈值,[公式:见文本])确保在连续预测 n 个预测后才更改类别。这两个函数都独立应用于最佳网络的预测。

结果

该方法在 50 个视频数据集上使用五重交叉验证进行评估,优化后的评估指标为加权-[公式:见文本]分数。最佳模型是 ResNet-50+LSTM,在三相分类中达到 0.84,在七步分类中达到 0.74。应用阈值平滑进一步提高了这些结果,三相分类达到 0.86,七步分类达到 0.75,同时大大降低了预测波动性。

结论

结果证实了既定方法可推广到内镜垂体手术,并且表明简单的时间平滑不仅可以降低预测波动性,而且还可以主动提高性能。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb8a/9307536/dc54e94e4603/11548_2022_2599_Fig1_HTML.jpg

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