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儿童胸部 CT 诊断参考水平与患者体型的关系。

Diagnostic reference levels for chest computed tomography in children as a function of patient size.

机构信息

Institute of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, University of Duisburg-Essen, Hufelandstraße 55, 45147, Essen, Germany.

Department of Diagnostic and Interventional Radiology, Neuroradiology, Asklepios Klinikum Harburg, Eißendorfer Pferdeweg 52, 21075, Hamburg, Germany.

出版信息

Pediatr Radiol. 2022 Jul;52(8):1446-1455. doi: 10.1007/s00247-022-05340-8. Epub 2022 Apr 5.

Abstract

BACKGROUND

Radiation exposures from computed tomography (CT) in children are inadequately studied. Diagnostic reference levels (DRLs) can help optimise radiation doses.

OBJECTIVE

To determine local DRLs for paediatric chest CT performed mainly on modern dual-source, multi-slice CT scanners as a function of patient size.

MATERIALS AND METHODS

Five hundred thirty-eight chest CT scans in 345 children under 15 years (y) of age (median age: 8 y, interquartile range [IQR]: 4-13 y) performed on four different CT scanners (38% on third-generation and 43% on second-generation dual-source CT) between November 2013 and December 2020 were retrospectively analysed. Examinations were grouped by water-equivalent diameter as a measure of patient size. DRLs for volume CT dose index (CTDI) and dose-length product (DLP) were determined for six different patient sizes and compared to national and European DRLs.

RESULTS

The DRLs for CTDI and DLP are determined for each patient size group as a function of water-equivalent diameter as follows: (I) < 13 cm (n = 22; median: age 7 months): 0.4 mGy, 7 mGy·cm; (II) 13 cm to less than 17 cm (n = 151; median: age 3 y): 1.2 mGy, 25 mGy·cm; (III) 17 cm to less than 21 cm (n = 211; median: age 8 y): 1.7 mGy, 44 mGy·cm; (IV) 21 cm to less than 25 cm (n = 97; median: age 14 y): 3.0 mGy, 88 mGy·cm; (V) 25 cm to less than 29 cm (n = 42; median: age 14 y): 4.5 mGy, 135 mGy·cm; (VI) ≥ 29 cm (n = 15; median: age 14 y): 8.0 mGy, 241 mGy·cm. Compared with corresponding age and weight groups, our size-based DRLs for DLP are 54% to 71% lower than national and 23% to 85% lower than European DRLs.

CONCLUSION

We developed DRLs for paediatric chest CT as a function of patient size with substantially lower values than national and European DRLs. Precise knowledge of size-based DRLs may assist other institutions in further dose optimisation in children.

摘要

背景

儿童 CT 检查的辐射暴露量研究不足。诊断参考水平(DRL)有助于优化辐射剂量。

目的

确定主要在现代双源、多层 CT 扫描仪上进行的儿科胸部 CT 的局部 DRL,作为患者体型的函数。

材料和方法

回顾性分析 2013 年 11 月至 2020 年 12 月期间在四台不同 CT 扫描仪上进行的 345 名年龄在 15 岁以下(中位数:8 岁,四分位距 [IQR]:4-13 岁)的 538 例胸部 CT 扫描(38%为第三代,43%为第二代双源 CT)。检查按水当量直径分组,作为患者体型的衡量标准。确定了六个不同患者体型组的容积 CT 剂量指数(CTDI)和剂量长度乘积(DLP)的 DRL,并与国家和欧洲的 DRL 进行了比较。

结果

根据水当量直径确定了每个患者体型组的 CTDI 和 DLP 的 DRL,具体如下:(I)<13cm(n=22;中位数:7 个月龄):0.4mGy,7mGy·cm;(II)13cm 至<17cm(n=151;中位数:3 岁):1.2mGy,25mGy·cm;(III)17cm 至<21cm(n=211;中位数:8 岁):1.7mGy,44mGy·cm;(IV)21cm 至<25cm(n=97;中位数:14 岁):3.0mGy,88mGy·cm;(V)25cm 至<29cm(n=42;中位数:14 岁):4.5mGy,135mGy·cm;(VI)≥29cm(n=15;中位数:14 岁):8.0mGy,241mGy·cm。与相应的年龄和体重组相比,我们基于体型的 DLP DRL 比国家和欧洲的 DRL 低 54%至 71%。

结论

我们根据患者体型制定了儿科胸部 CT 的 DRL,其值明显低于国家和欧洲的 DRL。对基于体型的 DRL 的准确了解可以帮助其他机构进一步优化儿童的剂量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0c0/9271112/b45a5b55a9bb/247_2022_5340_Fig1_HTML.jpg

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