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基于深度学习算法的肺癌病理人工智能辅助诊断模型。

Models of Artificial Intelligence-Assisted Diagnosis of Lung Cancer Pathology Based on Deep Learning Algorithms.

机构信息

The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510030, Guangdong, China.

出版信息

J Healthc Eng. 2022 Mar 26;2022:3972298. doi: 10.1155/2022/3972298. eCollection 2022.

DOI:10.1155/2022/3972298
PMID:35378943
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8976635/
Abstract

In this article, in order to explore the application of a diagnosis system for lung cancer, we use an auxiliary diagnostic system to predict and diagnose the good and evil attributes of chest CT pulmonary nodules. This research improves the new diagnosis method based on the convolutional neural network (CNN) and the recurrent neural network (RNN) and combines the dual effects of the two algorithms to process the classification of benign and malignant nodules. By collecting H-E-stained pathological slices of 652 patients' lung lesions from two hospitals between January 2018 and January 2019, the output results of the improved 3D U-net system and the consistent results of two-person reading were compared. This article analyzes the sensitivity, specificity, positive flammability rate, and negative flammability rate of different lung nodule detection methods. In addition, the artificial intelligence system's and the radiologist's judgment results of benign and malignant pulmonary nodules are used to draw ROC curves for further analysis. The improved model has an accuracy rate of 92.3% for predicting malignant lung nodules and an accuracy rate of 82.8% for benign lung nodules. The new diagnostic method using the convolutional neural network and the recurrent neural network can be very effective for improving the accuracy of predicting lung cancer diagnosis. It can play a very effective role in the disease prediction of lung cancer patients, thereby improving the treatment effect.

摘要

在本文中,为了探索肺癌诊断系统的应用,我们使用辅助诊断系统来预测和诊断胸部 CT 肺结节的良恶属性。本研究在卷积神经网络(CNN)和递归神经网络(RNN)的基础上进行了新的诊断方法的改进,结合了两种算法的双重作用,对良性和恶性结节进行分类。通过收集 2018 年 1 月至 2019 年 1 月期间两家医院的 652 例肺癌患者 H-E 染色病理切片,对比改进后的 3D U-net 系统和双人阅读的一致结果。本文分析了不同肺结节检测方法的敏感性、特异性、阳性预测率和阴性预测率。此外,还利用人工智能系统和放射科医生对良恶性肺结节的判断结果绘制 ROC 曲线进行进一步分析。改进后的模型对恶性肺结节的预测准确率为 92.3%,对良性肺结节的预测准确率为 82.8%。使用卷积神经网络和递归神经网络的新诊断方法可以非常有效地提高预测肺癌诊断的准确性。它可以在肺癌患者的疾病预测中发挥非常有效的作用,从而提高治疗效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b95/8976635/6e7ed78d0737/JHE2022-3972298.010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b95/8976635/e2a227364dd9/JHE2022-3972298.001.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b95/8976635/e2a227364dd9/JHE2022-3972298.001.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b95/8976635/99fa40825abf/JHE2022-3972298.006.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b95/8976635/591e232e8efe/JHE2022-3972298.008.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b95/8976635/6e7ed78d0737/JHE2022-3972298.010.jpg

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