Li Buhong, Lin Li
MOE Key Laboratory of OptoElectronic Science and Technology for Medicine, Fujian Provincial Key Laboratory for Photonics Technology, Fujian Normal University, Fuzhou, 350117, China.
Light Sci Appl. 2022 Apr 6;11(1):85. doi: 10.1038/s41377-022-00780-1.
Photodynamic therapy (PDT) for deep-seated lesion is seriously hindered by the limited depth of visible light penetration. Most recently, researchers have designed a genetically-encoded NanoLuc-miniSOG with internal light source for self-excitation, which is highly beneficial for deep PDT.
用于深部病变的光动力疗法(PDT)受到可见光穿透深度有限的严重阻碍。最近,研究人员设计了一种具有内部光源用于自激发的基因编码纳米荧光素酶-微型单氧酶(NanoLuc-miniSOG),这对深部光动力疗法非常有益。